Persistent and robust antibody responses to ChAdOx1-S Oxford-AstraZeneca (ChAdOx1-S, Covishield) SARS-CoV-2 vaccine observed in Ugandans across varied baseline immune profiles.

Persistent and robust antibody responses to ChAdOx1-S Oxford-AstraZeneca (ChAdOx1-S, Covishield) SARS-CoV-2 vaccine observed in Ugandans across varied baseline immune profiles.

Understanding SARS-CoV-2 vaccine-induced antibody responses in varied antigenic and serological prior exposures can guide optimal vaccination strategies for enhanced immunogenicity. We evaluated spike (S)-directed IgG, IgM, and IgA antibody optical densities (ODs) and concentrations to the two-dose...

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Bibliographic Details
Main Authors: Jennifer Serwanga, Gerald Kevin Oluka, Claire Baine, Violet Ankunda, Jackson Sembera, Laban Kato, Joseph Ssebwana Katende, Geoffrey Odoch, Betty Oliver Auma, Ben Gombe, COVID-19 Immunoprofiling Team, Monica Musenero, Pontiano Kaleebu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0303113
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