Synthesis and anti-microbial evaluation with in silico studies of novel 2-aminothiazole benzohydrazide derivatives

Synthesis and anti-microbial evaluation with in silico studies of novel 2-aminothiazole benzohydrazide derivatives

Abstract Background The development of novel anti-microbial drugs for multidrug-resistant (MDR) is a significant challenge. This study aimed to synthesize various derivatives of (Z)-4-(2-aminothiazol-5-yl)-N-benzohydrazide (DT01-DT10) that are effective against a wide variety of anti-bacterial and a...

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Bibliographic Details
Main Authors: S. Amrutha, Paramita Das, Anjali Nayak, Supratip Laha, Sharmina Begum, Sakshi Bhardwaj
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
2-Aminothiazole
Anti-microbial
Molecular docking
Simulation
MIC
Cytotoxicity
Online Access:https://doi.org/10.1186/s43094-024-00759-2
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