Cyclophosphamide: An Alternative Treatment in Crohn’s Disease

lmmunosuppressive therapy in the form of 6-mercaptopurine has shown a 66% efficacy in severe, debilitating, highly corticosteroid dependent Crohn’s disease. Nevertheless this medication has some important side effects such as nausea, vomiting, leukopenia and pancreatitis. Two patients are presented...

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Main Authors: Gilles Lapointe, Aubin Charbonneau
Format: Article
Language:English
Published: Wiley 1989-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1989/498156
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author Gilles Lapointe
Aubin Charbonneau
author_facet Gilles Lapointe
Aubin Charbonneau
author_sort Gilles Lapointe
collection DOAJ
description lmmunosuppressive therapy in the form of 6-mercaptopurine has shown a 66% efficacy in severe, debilitating, highly corticosteroid dependent Crohn’s disease. Nevertheless this medication has some important side effects such as nausea, vomiting, leukopenia and pancreatitis. Two patients are presented who, suffering from severe Crohn’s disease, were unable to tolerate 6-mercaptopurine but showed an amazing improvement with cyclophosphamide.
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publishDate 1989-01-01
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series Canadian Journal of Gastroenterology
spelling doaj-art-97b5a3bf6d054fe4b0ea1e57e9709f652025-02-03T01:26:31ZengWileyCanadian Journal of Gastroenterology0835-79001989-01-013517517810.1155/1989/498156Cyclophosphamide: An Alternative Treatment in Crohn’s DiseaseGilles Lapointe0Aubin Charbonneau1Division of Gastroenterology, Chicoutimi Hospital, Chicoutimi, Qubeéc, CanadaDivision of Gastroenterology, Chicoutimi Hospital, Chicoutimi, Qubeéc, Canadalmmunosuppressive therapy in the form of 6-mercaptopurine has shown a 66% efficacy in severe, debilitating, highly corticosteroid dependent Crohn’s disease. Nevertheless this medication has some important side effects such as nausea, vomiting, leukopenia and pancreatitis. Two patients are presented who, suffering from severe Crohn’s disease, were unable to tolerate 6-mercaptopurine but showed an amazing improvement with cyclophosphamide.http://dx.doi.org/10.1155/1989/498156
spellingShingle Gilles Lapointe
Aubin Charbonneau
Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
Canadian Journal of Gastroenterology
title Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_full Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_fullStr Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_full_unstemmed Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_short Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_sort cyclophosphamide an alternative treatment in crohn s disease
url http://dx.doi.org/10.1155/1989/498156
work_keys_str_mv AT gilleslapointe cyclophosphamideanalternativetreatmentincrohnsdisease
AT aubincharbonneau cyclophosphamideanalternativetreatmentincrohnsdisease