“Human Babesiosis”: An Emerging Transfusion Dilemma
Babesiosis, a common disease of animals, can infect humans via vector “tick bite”, particularly in endemic areas. The recent reports of fatal cases in Hepatitis C and postliver transplant patients resulting from transfusion of contaminated blood should alert the medical profession regarding this eme...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2012/431761 |
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| _version_ | 1832550710639591424 |
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| author | Helieh S. Oz Karin H. Westlund |
| author_facet | Helieh S. Oz Karin H. Westlund |
| author_sort | Helieh S. Oz |
| collection | DOAJ |
| description | Babesiosis, a common disease of animals, can infect humans via vector “tick bite”, particularly in endemic areas. The recent reports of fatal cases in Hepatitis C and postliver transplant patients resulting from transfusion of contaminated blood should alert the medical profession regarding this emerging dilemma in endemic as well as nonendemic areas and the need for accurate blood screening for transfusion. Here, we illustrate different stages of the parasite lifecycle, progression of babesiosis in animal model, some aspects of pathologic outcomes, ongoing therapeutic modalities, and a feasible Acridine Orange fluorescent methodology for the diagnostic evaluation of blood samples. |
| format | Article |
| id | doaj-art-97a4ae2815c4477fb7cf09189fcd554f |
| institution | Kabale University |
| issn | 2090-3448 2090-3456 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hepatology |
| spelling | doaj-art-97a4ae2815c4477fb7cf09189fcd554f2025-02-03T06:06:04ZengWileyInternational Journal of Hepatology2090-34482090-34562012-01-01201210.1155/2012/431761431761“Human Babesiosis”: An Emerging Transfusion DilemmaHelieh S. Oz0Karin H. Westlund1Department of Physiology, University of Kentucky Medical Center, Lexington, KY 40536, USADepartment of Physiology, University of Kentucky Medical Center, Lexington, KY 40536, USABabesiosis, a common disease of animals, can infect humans via vector “tick bite”, particularly in endemic areas. The recent reports of fatal cases in Hepatitis C and postliver transplant patients resulting from transfusion of contaminated blood should alert the medical profession regarding this emerging dilemma in endemic as well as nonendemic areas and the need for accurate blood screening for transfusion. Here, we illustrate different stages of the parasite lifecycle, progression of babesiosis in animal model, some aspects of pathologic outcomes, ongoing therapeutic modalities, and a feasible Acridine Orange fluorescent methodology for the diagnostic evaluation of blood samples.http://dx.doi.org/10.1155/2012/431761 |
| spellingShingle | Helieh S. Oz Karin H. Westlund “Human Babesiosis”: An Emerging Transfusion Dilemma International Journal of Hepatology |
| title | “Human Babesiosis”: An Emerging Transfusion Dilemma |
| title_full | “Human Babesiosis”: An Emerging Transfusion Dilemma |
| title_fullStr | “Human Babesiosis”: An Emerging Transfusion Dilemma |
| title_full_unstemmed | “Human Babesiosis”: An Emerging Transfusion Dilemma |
| title_short | “Human Babesiosis”: An Emerging Transfusion Dilemma |
| title_sort | human babesiosis an emerging transfusion dilemma |
| url | http://dx.doi.org/10.1155/2012/431761 |
| work_keys_str_mv | AT heliehsoz humanbabesiosisanemergingtransfusiondilemma AT karinhwestlund humanbabesiosisanemergingtransfusiondilemma |