An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults
We investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt (Notophthalmus viridescens) efts and adults. Several other species, such as Pleurodeles waltl and Echinotriton andersoni, have granular glands concentrated in brig...
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Wiley
2018-01-01
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Series: | Journal of Toxicology |
Online Access: | http://dx.doi.org/10.1155/2018/9196865 |
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author | Mackenzie M. Spicer Amber N. Stokes Trevor L. Chapman Edmund D. Brodie Edmund D. Brodie Brian G. Gall |
author_facet | Mackenzie M. Spicer Amber N. Stokes Trevor L. Chapman Edmund D. Brodie Edmund D. Brodie Brian G. Gall |
author_sort | Mackenzie M. Spicer |
collection | DOAJ |
description | We investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt (Notophthalmus viridescens) efts and adults. Several other species, such as Pleurodeles waltl and Echinotriton andersoni, have granular glands concentrated in brightly pigmented regions on the dorsum, and thus we hypothesized that the red dorsal spots of Eastern newts may also possess higher levels of TTX than the surrounding skin. We found no difference between the concentrations of TTX in the red spots as compared to neighboring skin lacking these spots in either efts or adults. However, efts with more red dorsal spots had elevated TTX levels relative to efts with fewer spots. |
format | Article |
id | doaj-art-9793f603453249faaafdddb6cb562ba6 |
institution | Kabale University |
issn | 1687-8191 1687-8205 |
language | English |
publishDate | 2018-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Toxicology |
spelling | doaj-art-9793f603453249faaafdddb6cb562ba62025-02-03T01:21:30ZengWileyJournal of Toxicology1687-81911687-82052018-01-01201810.1155/2018/91968659196865An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and AdultsMackenzie M. Spicer0Amber N. Stokes1Trevor L. Chapman2Edmund D. Brodie3Edmund D. Brodie4Brian G. Gall5Department of Pharmacology, The University of Iowa, Iowa City, Iowa 52242, USADepartment of Biology, California State University, Bakersfield, CA 93311, USADepartment of Biology, East Tennessee State University, Johnson City, TN 37614, USADepartment of Biology, Utah State University, 5305 Old Main Hill, Logan, UT 84322, USADepartment of Biology, University of Virginia, PO Box 400328, Charlottesville, VA 22904, USADepartment of Biology, Hanover College, 517 Ball Drive, Hanover, IN 47243, USAWe investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt (Notophthalmus viridescens) efts and adults. Several other species, such as Pleurodeles waltl and Echinotriton andersoni, have granular glands concentrated in brightly pigmented regions on the dorsum, and thus we hypothesized that the red dorsal spots of Eastern newts may also possess higher levels of TTX than the surrounding skin. We found no difference between the concentrations of TTX in the red spots as compared to neighboring skin lacking these spots in either efts or adults. However, efts with more red dorsal spots had elevated TTX levels relative to efts with fewer spots.http://dx.doi.org/10.1155/2018/9196865 |
spellingShingle | Mackenzie M. Spicer Amber N. Stokes Trevor L. Chapman Edmund D. Brodie Edmund D. Brodie Brian G. Gall An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults Journal of Toxicology |
title | An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults |
title_full | An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults |
title_fullStr | An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults |
title_full_unstemmed | An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults |
title_short | An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults |
title_sort | investigation into tetrodotoxin ttx levels associated with the red dorsal spots in eastern newt notophthalmus viridescens efts and adults |
url | http://dx.doi.org/10.1155/2018/9196865 |
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