An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults

We investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt (Notophthalmus viridescens) efts and adults. Several other species, such as Pleurodeles waltl and Echinotriton andersoni, have granular glands concentrated in brig...

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Main Authors: Mackenzie M. Spicer, Amber N. Stokes, Trevor L. Chapman, Edmund D. Brodie, Brian G. Gall
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2018/9196865
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author Mackenzie M. Spicer
Amber N. Stokes
Trevor L. Chapman
Edmund D. Brodie
Edmund D. Brodie
Brian G. Gall
author_facet Mackenzie M. Spicer
Amber N. Stokes
Trevor L. Chapman
Edmund D. Brodie
Edmund D. Brodie
Brian G. Gall
author_sort Mackenzie M. Spicer
collection DOAJ
description We investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt (Notophthalmus viridescens) efts and adults. Several other species, such as Pleurodeles waltl and Echinotriton andersoni, have granular glands concentrated in brightly pigmented regions on the dorsum, and thus we hypothesized that the red dorsal spots of Eastern newts may also possess higher levels of TTX than the surrounding skin. We found no difference between the concentrations of TTX in the red spots as compared to neighboring skin lacking these spots in either efts or adults. However, efts with more red dorsal spots had elevated TTX levels relative to efts with fewer spots.
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institution Kabale University
issn 1687-8191
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language English
publishDate 2018-01-01
publisher Wiley
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series Journal of Toxicology
spelling doaj-art-9793f603453249faaafdddb6cb562ba62025-02-03T01:21:30ZengWileyJournal of Toxicology1687-81911687-82052018-01-01201810.1155/2018/91968659196865An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and AdultsMackenzie M. Spicer0Amber N. Stokes1Trevor L. Chapman2Edmund D. Brodie3Edmund D. Brodie4Brian G. Gall5Department of Pharmacology, The University of Iowa, Iowa City, Iowa 52242, USADepartment of Biology, California State University, Bakersfield, CA 93311, USADepartment of Biology, East Tennessee State University, Johnson City, TN 37614, USADepartment of Biology, Utah State University, 5305 Old Main Hill, Logan, UT 84322, USADepartment of Biology, University of Virginia, PO Box 400328, Charlottesville, VA 22904, USADepartment of Biology, Hanover College, 517 Ball Drive, Hanover, IN 47243, USAWe investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt (Notophthalmus viridescens) efts and adults. Several other species, such as Pleurodeles waltl and Echinotriton andersoni, have granular glands concentrated in brightly pigmented regions on the dorsum, and thus we hypothesized that the red dorsal spots of Eastern newts may also possess higher levels of TTX than the surrounding skin. We found no difference between the concentrations of TTX in the red spots as compared to neighboring skin lacking these spots in either efts or adults. However, efts with more red dorsal spots had elevated TTX levels relative to efts with fewer spots.http://dx.doi.org/10.1155/2018/9196865
spellingShingle Mackenzie M. Spicer
Amber N. Stokes
Trevor L. Chapman
Edmund D. Brodie
Edmund D. Brodie
Brian G. Gall
An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults
Journal of Toxicology
title An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults
title_full An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults
title_fullStr An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults
title_full_unstemmed An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults
title_short An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults
title_sort investigation into tetrodotoxin ttx levels associated with the red dorsal spots in eastern newt notophthalmus viridescens efts and adults
url http://dx.doi.org/10.1155/2018/9196865
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