Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the Literature

A 31-year-old Canadian Aboriginal man from northwestern Ontario presented with left upper quadrant pain and a tender left upper quadrant mass. Evaluation with a computed tomography scan showed multiple lesions within the spleen, a collection between the splenic tip and splenic flexure of the colon,...

Full description

Saved in:
Bibliographic Details
Main Authors: Sami Al-Nassar, Tracy MacNair, Jeremy Lipschitz, Howard Greenberg, Elly Trepman, Sate Hamza, John M Embil
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2010/679604
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832567810676490240
author Sami Al-Nassar
Tracy MacNair
Jeremy Lipschitz
Howard Greenberg
Elly Trepman
Sate Hamza
John M Embil
author_facet Sami Al-Nassar
Tracy MacNair
Jeremy Lipschitz
Howard Greenberg
Elly Trepman
Sate Hamza
John M Embil
author_sort Sami Al-Nassar
collection DOAJ
description A 31-year-old Canadian Aboriginal man from northwestern Ontario presented with left upper quadrant pain and a tender left upper quadrant mass. Evaluation with a computed tomography scan showed multiple lesions within the spleen, a collection between the splenic tip and splenic flexure of the colon, and several small adrenal lesions. Computed tomographic-guided needle biopsy showed necrotizing granulomatous inflammation and multinucleated giant cells. Gomori’s methenamine silver stain showed broad-based budding yeast consistent with Blastomyces dermatitidis. Abdominal symptoms resolved after two months of oral itraconazole. Multiple splenic abscesses are a rare presentation of blastomycosis and should be considered in the differential diagnosis of left upper quadrant abdominal pain in a patient with a history of travel or residence in a region endemic for B dermatitidis.
format Article
id doaj-art-976bc5a879fe41398bbe757c7ddfab04
institution Kabale University
issn 1712-9532
language English
publishDate 2010-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-976bc5a879fe41398bbe757c7ddfab042025-02-03T01:00:31ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322010-01-01211535610.1155/2010/679604Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the LiteratureSami Al-Nassar0Tracy MacNair1Jeremy Lipschitz2Howard Greenberg3Elly Trepman4Sate Hamza5John M Embil6Department of Surgery, King Saud University, Riyadh, Saudi ArabiaDepartment of Radiology, Diagnostic Services, Boundary Trails Health Centre, Winkler, CanadaDepartment of Surgery, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Diagnostic Imaging, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Pathology, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, CanadaA 31-year-old Canadian Aboriginal man from northwestern Ontario presented with left upper quadrant pain and a tender left upper quadrant mass. Evaluation with a computed tomography scan showed multiple lesions within the spleen, a collection between the splenic tip and splenic flexure of the colon, and several small adrenal lesions. Computed tomographic-guided needle biopsy showed necrotizing granulomatous inflammation and multinucleated giant cells. Gomori’s methenamine silver stain showed broad-based budding yeast consistent with Blastomyces dermatitidis. Abdominal symptoms resolved after two months of oral itraconazole. Multiple splenic abscesses are a rare presentation of blastomycosis and should be considered in the differential diagnosis of left upper quadrant abdominal pain in a patient with a history of travel or residence in a region endemic for B dermatitidis.http://dx.doi.org/10.1155/2010/679604
spellingShingle Sami Al-Nassar
Tracy MacNair
Jeremy Lipschitz
Howard Greenberg
Elly Trepman
Sate Hamza
John M Embil
Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the Literature
Canadian Journal of Infectious Diseases and Medical Microbiology
title Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the Literature
title_full Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the Literature
title_fullStr Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the Literature
title_full_unstemmed Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the Literature
title_short Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the Literature
title_sort blastomycosis presenting as multiple splenic abscesses case report and review of the literature
url http://dx.doi.org/10.1155/2010/679604
work_keys_str_mv AT samialnassar blastomycosispresentingasmultiplesplenicabscessescasereportandreviewoftheliterature
AT tracymacnair blastomycosispresentingasmultiplesplenicabscessescasereportandreviewoftheliterature
AT jeremylipschitz blastomycosispresentingasmultiplesplenicabscessescasereportandreviewoftheliterature
AT howardgreenberg blastomycosispresentingasmultiplesplenicabscessescasereportandreviewoftheliterature
AT ellytrepman blastomycosispresentingasmultiplesplenicabscessescasereportandreviewoftheliterature
AT satehamza blastomycosispresentingasmultiplesplenicabscessescasereportandreviewoftheliterature
AT johnmembil blastomycosispresentingasmultiplesplenicabscessescasereportandreviewoftheliterature