A genome-wide association study identifies new loci associated with response to SARS-CoV-2 mRNA-1273 vaccine in a cohort of healthy healthcare workers

A genome-wide association study identifies new loci associated with response to SARS-CoV-2 mRNA-1273 vaccine in a cohort of healthy healthcare workers

IntroductionThe COVID-19 pandemic had significant global public health consequences, affecting over 200 countries and regions by 2020. The development and efficacy of specific vaccines, such as the mRNA-1273 (Spikevax®) vaccine developed by Moderna Inc., have substantially reduced the impact of the...

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Bibliographic Details
Main Authors: Antonio José Cabrera-Serrano, Lucía Ruiz-Durán, Juan Francisco Gutiérrez-Bautista, María Carretero-Fernández, Rob ter Horst, Yang Li, Fernando Jesús Reyes-Zurita, Francisco José García-Verdejo, Mihai G. Netea, Pedro Sánchez-Rovira, Miguel Ángel López-Nevot, Antonio Sampedro, Juan Sainz
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
GWAS
circulating IgG levels
genetic variants
IgG decay
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1639825/full
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