Streptococcus abundance and oral site tropism in humans and non-human primates reflects host and lifestyle differences
Abstract The genus Streptococcus is highly diverse and a core member of the primate oral microbiome. Streptococcus species are grouped into at least eight phylogenetically-supported clades, five of which are found almost exclusively in the oral cavity. We explored the dominant Streptococcus phylogen...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | npj Biofilms and Microbiomes |
| Online Access: | https://doi.org/10.1038/s41522-024-00642-1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832594990464761856 |
|---|---|
| author | Irina M. Velsko Christina Warinner |
| author_facet | Irina M. Velsko Christina Warinner |
| author_sort | Irina M. Velsko |
| collection | DOAJ |
| description | Abstract The genus Streptococcus is highly diverse and a core member of the primate oral microbiome. Streptococcus species are grouped into at least eight phylogenetically-supported clades, five of which are found almost exclusively in the oral cavity. We explored the dominant Streptococcus phylogenetic clades in samples from multiple oral sites and from ancient and modern-day humans and non-human primates and found that clade dominance is conserved across human oral sites, with most Streptococcus reads assigned to species falling in the Sanguinis or Mitis clades. However, minor differences in the presence and abundance of individual species within each clade differentiated human lifestyles, with loss of S. sinensis appearing to correlate with toothbrushing. Of the non-human primates, only baboons show clade abundance patterns similar to humans, suggesting that a habitat and diet similar to that of early humans may favor the growth of Sanguinis and Mitis clade species. |
| format | Article |
| id | doaj-art-97655ddef5fa403583d281ddec8a0f30 |
| institution | Kabale University |
| issn | 2055-5008 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Biofilms and Microbiomes |
| spelling | doaj-art-97655ddef5fa403583d281ddec8a0f302025-01-19T12:12:16ZengNature Portfolionpj Biofilms and Microbiomes2055-50082025-01-0111111310.1038/s41522-024-00642-1Streptococcus abundance and oral site tropism in humans and non-human primates reflects host and lifestyle differencesIrina M. Velsko0Christina Warinner1Department of Archaeogenetics, Max Planck Institute for Evolutionary AnthropologyDepartment of Archaeogenetics, Max Planck Institute for Evolutionary AnthropologyAbstract The genus Streptococcus is highly diverse and a core member of the primate oral microbiome. Streptococcus species are grouped into at least eight phylogenetically-supported clades, five of which are found almost exclusively in the oral cavity. We explored the dominant Streptococcus phylogenetic clades in samples from multiple oral sites and from ancient and modern-day humans and non-human primates and found that clade dominance is conserved across human oral sites, with most Streptococcus reads assigned to species falling in the Sanguinis or Mitis clades. However, minor differences in the presence and abundance of individual species within each clade differentiated human lifestyles, with loss of S. sinensis appearing to correlate with toothbrushing. Of the non-human primates, only baboons show clade abundance patterns similar to humans, suggesting that a habitat and diet similar to that of early humans may favor the growth of Sanguinis and Mitis clade species.https://doi.org/10.1038/s41522-024-00642-1 |
| spellingShingle | Irina M. Velsko Christina Warinner Streptococcus abundance and oral site tropism in humans and non-human primates reflects host and lifestyle differences npj Biofilms and Microbiomes |
| title | Streptococcus abundance and oral site tropism in humans and non-human primates reflects host and lifestyle differences |
| title_full | Streptococcus abundance and oral site tropism in humans and non-human primates reflects host and lifestyle differences |
| title_fullStr | Streptococcus abundance and oral site tropism in humans and non-human primates reflects host and lifestyle differences |
| title_full_unstemmed | Streptococcus abundance and oral site tropism in humans and non-human primates reflects host and lifestyle differences |
| title_short | Streptococcus abundance and oral site tropism in humans and non-human primates reflects host and lifestyle differences |
| title_sort | streptococcus abundance and oral site tropism in humans and non human primates reflects host and lifestyle differences |
| url | https://doi.org/10.1038/s41522-024-00642-1 |
| work_keys_str_mv | AT irinamvelsko streptococcusabundanceandoralsitetropisminhumansandnonhumanprimatesreflectshostandlifestyledifferences AT christinawarinner streptococcusabundanceandoralsitetropisminhumansandnonhumanprimatesreflectshostandlifestyledifferences |