The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats
ABSTRACTAnabolic steroids are testosterone derivatives through which anabolic effects are maintained and androgenic effects are minimized. The use of ergogenic agents is increasing among athletes for doping in order to increase physical performance and change external image. The objective of this st...
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Selcuk University Press
2019-09-01
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| Series: | Türk Spor ve Egzersiz Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/812541 |
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| author | Ali Sarı Sefa Lök |
| author_facet | Ali Sarı Sefa Lök |
| author_sort | Ali Sarı |
| collection | DOAJ |
| description | ABSTRACTAnabolic
steroids are testosterone derivatives through which anabolic effects are
maintained and androgenic effects are minimized. The use of ergogenic agents is
increasing among athletes for doping in order to increase physical performance
and change external image. The objective of this study was to determine effects
of trenbolone supplement administered on running rats for 4 weeks on extremity
bones. The study was conducted with 28 male Wistar rats aged 28 days with a
mean weight of 61,80 g supplied from the Selcuk University Experimental Medical
Research and Application Center. The rate were divided into 4 groups as C
(Controls), E (Exercise), T (Trenbolone), and TE (trenbolone + Exercise). The
trial period lasted 4 weeks. Supply, care, feeding, and experimental
applications of rats were performed in the Selcuk University Experimental
Medical Research and Application Center. Anterior and posterior extremities’
bones were dissected and exposed, and the humerus and femur bones exposed were
dried. Length, corpus thickness, cortex thickness, and medulla diameter points
were determined and the necessary measures were taken. The results are
expressed as mean ± SD. ANOVA and Duncan tests were used for the comparison of
data. p lt;0.05 values were considered statistically significant. The mean
femoral length was found as 31.31 ± 0.69 in the rats in Group T, 31.46±0.72 in
Group E, 31.51±0.58 in Group TE, and 31.48 ± 0.71 in Group C (controls).
Examining the mean femoral lengths of Groups T, E, TE and C; the mean femoral
length in Group T was numerically higher than that of the Groups E, TE and C,
although the difference was not statistically significant (F:0.112; p:0.637).
The mean humerus length was found as 24.93 ± 0.59 in the rats in Group T, 24.96±0.68
in Group E, 25.33±0.81 in Group TE, and 25.29±0.77 in Group C (controls).
Examining the mean humerus lengths of Groups T, E, TE and C; the mean humerus
length in Group T was numerically higher than that of the Groups E, TE and C,
although the difference was not statistically significant (F:0.608; p:0.355).
We found that the mean values of corpus and cortex thickness, and medullary
diameters were similar in the Groups T, E, TE, and C, and the differences were
not statistically significant (p gt;0.05). Results of
this study indicate that trenbolone supplement may lead to early epiphyseal
closure in femur and humerus bones of rats, ceasing the increase in their
length. We believe that the results obtained from this trenbolone trial will
provide important data to the studies that will be conducted on anabolic
androgenic steroids.
Key
words: Anabolic Androgenic Steroid, Trenbolone, Rat, Femur, Humerus |
| format | Article |
| id | doaj-art-9752df40cfc54dc2804e943af171ce7f |
| institution | Kabale University |
| issn | 2147-5652 |
| language | English |
| publishDate | 2019-09-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Türk Spor ve Egzersiz Dergisi |
| spelling | doaj-art-9752df40cfc54dc2804e943af171ce7f2025-02-03T03:38:41ZengSelcuk University PressTürk Spor ve Egzersiz Dergisi2147-56522019-09-0121236637110.15314/tsed.555015154The Effects of Trenbolone Supplementation on The Extremity Bones in Running RatsAli Sarı0Sefa Lök1SELCUK UNIVERSITY, INSTITUTE OF HEALTH SCIENCESFACULTY OF SPORTS SCIENCESABSTRACTAnabolic steroids are testosterone derivatives through which anabolic effects are maintained and androgenic effects are minimized. The use of ergogenic agents is increasing among athletes for doping in order to increase physical performance and change external image. The objective of this study was to determine effects of trenbolone supplement administered on running rats for 4 weeks on extremity bones. The study was conducted with 28 male Wistar rats aged 28 days with a mean weight of 61,80 g supplied from the Selcuk University Experimental Medical Research and Application Center. The rate were divided into 4 groups as C (Controls), E (Exercise), T (Trenbolone), and TE (trenbolone + Exercise). The trial period lasted 4 weeks. Supply, care, feeding, and experimental applications of rats were performed in the Selcuk University Experimental Medical Research and Application Center. Anterior and posterior extremities’ bones were dissected and exposed, and the humerus and femur bones exposed were dried. Length, corpus thickness, cortex thickness, and medulla diameter points were determined and the necessary measures were taken. The results are expressed as mean ± SD. ANOVA and Duncan tests were used for the comparison of data. p lt;0.05 values were considered statistically significant. The mean femoral length was found as 31.31 ± 0.69 in the rats in Group T, 31.46±0.72 in Group E, 31.51±0.58 in Group TE, and 31.48 ± 0.71 in Group C (controls). Examining the mean femoral lengths of Groups T, E, TE and C; the mean femoral length in Group T was numerically higher than that of the Groups E, TE and C, although the difference was not statistically significant (F:0.112; p:0.637). The mean humerus length was found as 24.93 ± 0.59 in the rats in Group T, 24.96±0.68 in Group E, 25.33±0.81 in Group TE, and 25.29±0.77 in Group C (controls). Examining the mean humerus lengths of Groups T, E, TE and C; the mean humerus length in Group T was numerically higher than that of the Groups E, TE and C, although the difference was not statistically significant (F:0.608; p:0.355). We found that the mean values of corpus and cortex thickness, and medullary diameters were similar in the Groups T, E, TE, and C, and the differences were not statistically significant (p gt;0.05). Results of this study indicate that trenbolone supplement may lead to early epiphyseal closure in femur and humerus bones of rats, ceasing the increase in their length. We believe that the results obtained from this trenbolone trial will provide important data to the studies that will be conducted on anabolic androgenic steroids. Key words: Anabolic Androgenic Steroid, Trenbolone, Rat, Femur, Humerushttps://dergipark.org.tr/tr/download/article-file/812541anabolic androgenic steroidtrenbolonerat |
| spellingShingle | Ali Sarı Sefa Lök The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats Türk Spor ve Egzersiz Dergisi anabolic androgenic steroid trenbolone rat |
| title | The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats |
| title_full | The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats |
| title_fullStr | The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats |
| title_full_unstemmed | The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats |
| title_short | The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats |
| title_sort | effects of trenbolone supplementation on the extremity bones in running rats |
| topic | anabolic androgenic steroid trenbolone rat |
| url | https://dergipark.org.tr/tr/download/article-file/812541 |
| work_keys_str_mv | AT alisarı theeffectsoftrenbolonesupplementationontheextremitybonesinrunningrats AT sefalok theeffectsoftrenbolonesupplementationontheextremitybonesinrunningrats AT alisarı effectsoftrenbolonesupplementationontheextremitybonesinrunningrats AT sefalok effectsoftrenbolonesupplementationontheextremitybonesinrunningrats |