A Lethal Complication after Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma
Background. The current standard of care for patients with large or multinodular noninvasive hepatocellular carcinoma is conventional transarterial chemoembolization (TACE). TACE may also be performed with drug-eluting beads, but serious complications of this procedure have been reported. Methods....
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2015/873601 |
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| author | Adriana Toro Gaetano Bertino Maria Concetta Arcerito Maurizio Mannnino Annalisa Ardiri Domenico Patane’ Isidoro Di Carlo |
| author_facet | Adriana Toro Gaetano Bertino Maria Concetta Arcerito Maurizio Mannnino Annalisa Ardiri Domenico Patane’ Isidoro Di Carlo |
| author_sort | Adriana Toro |
| collection | DOAJ |
| description | Background. The current standard of care for patients with large or multinodular noninvasive hepatocellular carcinoma is conventional transarterial chemoembolization (TACE). TACE may also be performed with drug-eluting beads, but serious complications of this procedure have been reported. Methods. Aim of this report is to present a patient affected by multifocal HCC who underwent TACE with drug-eluting bead (DEB-TACE). Results. Following the procedure the patient developed a hepatic abscess and biliobronchial fistula resulting in adult respiratory distress syndrome and death. Conclusion. We speculate that DEB-TACE has a prolonged effect on the tumor and the surrounding liver, resulting in progressive enlargement of the necrotic area. This activity that can extend to the surrounding healthy hepatic tissues may continue indefinitely. |
| format | Article |
| id | doaj-art-9750900d320e4278af9ae8b681a21445 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-9750900d320e4278af9ae8b681a214452025-02-03T01:22:23ZengWileyCase Reports in Surgery2090-69002090-69192015-01-01201510.1155/2015/873601873601A Lethal Complication after Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular CarcinomaAdriana Toro0Gaetano Bertino1Maria Concetta Arcerito2Maurizio Mannnino3Annalisa Ardiri4Domenico Patane’5Isidoro Di Carlo6Department of Surgical Sciences, Organ Transplantation and Advanced Technologies, University of Catania, Cannizzaro Hospital, 95100 Catania, ItalyDepartment of Internal Medicine and Systemic Disease, Hepatology Unit, University of Catania, S. Marta Hospital, 95100 Catania, ItalyDepartment of Emergency, Vittorio Emanuele Hospital, 93012 Gela, ItalyDepartment of Surgical Sciences, Organ Transplantation and Advanced Technologies, University of Catania, Cannizzaro Hospital, 95100 Catania, ItalyDepartment of Internal Medicine and Systemic Disease, Hepatology Unit, University of Catania, S. Marta Hospital, 95100 Catania, ItalyDepartment of Radiology, Cannizzaro Hospital, 95100 Catania, ItalyDepartment of Surgical Sciences, Organ Transplantation and Advanced Technologies, University of Catania, Cannizzaro Hospital, 95100 Catania, ItalyBackground. The current standard of care for patients with large or multinodular noninvasive hepatocellular carcinoma is conventional transarterial chemoembolization (TACE). TACE may also be performed with drug-eluting beads, but serious complications of this procedure have been reported. Methods. Aim of this report is to present a patient affected by multifocal HCC who underwent TACE with drug-eluting bead (DEB-TACE). Results. Following the procedure the patient developed a hepatic abscess and biliobronchial fistula resulting in adult respiratory distress syndrome and death. Conclusion. We speculate that DEB-TACE has a prolonged effect on the tumor and the surrounding liver, resulting in progressive enlargement of the necrotic area. This activity that can extend to the surrounding healthy hepatic tissues may continue indefinitely.http://dx.doi.org/10.1155/2015/873601 |
| spellingShingle | Adriana Toro Gaetano Bertino Maria Concetta Arcerito Maurizio Mannnino Annalisa Ardiri Domenico Patane’ Isidoro Di Carlo A Lethal Complication after Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma Case Reports in Surgery |
| title | A Lethal Complication after Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma |
| title_full | A Lethal Complication after Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma |
| title_fullStr | A Lethal Complication after Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma |
| title_full_unstemmed | A Lethal Complication after Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma |
| title_short | A Lethal Complication after Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma |
| title_sort | lethal complication after transarterial chemoembolization with drug eluting beads for hepatocellular carcinoma |
| url | http://dx.doi.org/10.1155/2015/873601 |
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