Role of microRNAs in Stroke and Poststroke Depression
microRNAs (miRNA), a sort of noncoding RNAs widely distributed in eukaryotic cells, could regulate gene expression by inhibiting transcription or translation. They were involved in important physiological and pathological processes including growth, development, and occurrence and progression of dis...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/459692 |
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| _version_ | 1832563720265400320 |
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| author | Han Yan Min Fang Xue-Yuan Liu |
| author_facet | Han Yan Min Fang Xue-Yuan Liu |
| author_sort | Han Yan |
| collection | DOAJ |
| description | microRNAs (miRNA), a sort of noncoding RNAs widely distributed in eukaryotic cells, could regulate gene expression by inhibiting transcription or translation. They were involved in important physiological and pathological processes including growth, development, and occurrence and progression of diseases. miRNAs are crucial for the development of the nervous system. Recent studies have demonstrated that some miRNAs play important roles in the occurrence and development of ischemic cerebrovascular diseases such as stroke and were also involved in the occurrence and development of poststroke depression (PSD). Herein, studies on the role of miRNAs in the cerebral ischemia and PSD were reviewed, and results may be helpful for the diagnosis and prognosis of cerebral ischemia and PSD with miRNAs in clinical practice. |
| format | Article |
| id | doaj-art-973711454eb746f391bcd1bdaaf1aae4 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-973711454eb746f391bcd1bdaaf1aae42025-02-03T01:12:39ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/459692459692Role of microRNAs in Stroke and Poststroke DepressionHan Yan0Min Fang1Xue-Yuan Liu2Department of Neurology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Middle Yanchang Road No. 301, Zhabei District, Shanghai 200072, ChinaDepartment of Neurology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Middle Yanchang Road No. 301, Zhabei District, Shanghai 200072, ChinaDepartment of Neurology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Middle Yanchang Road No. 301, Zhabei District, Shanghai 200072, ChinamicroRNAs (miRNA), a sort of noncoding RNAs widely distributed in eukaryotic cells, could regulate gene expression by inhibiting transcription or translation. They were involved in important physiological and pathological processes including growth, development, and occurrence and progression of diseases. miRNAs are crucial for the development of the nervous system. Recent studies have demonstrated that some miRNAs play important roles in the occurrence and development of ischemic cerebrovascular diseases such as stroke and were also involved in the occurrence and development of poststroke depression (PSD). Herein, studies on the role of miRNAs in the cerebral ischemia and PSD were reviewed, and results may be helpful for the diagnosis and prognosis of cerebral ischemia and PSD with miRNAs in clinical practice.http://dx.doi.org/10.1155/2013/459692 |
| spellingShingle | Han Yan Min Fang Xue-Yuan Liu Role of microRNAs in Stroke and Poststroke Depression The Scientific World Journal |
| title | Role of microRNAs in Stroke and Poststroke Depression |
| title_full | Role of microRNAs in Stroke and Poststroke Depression |
| title_fullStr | Role of microRNAs in Stroke and Poststroke Depression |
| title_full_unstemmed | Role of microRNAs in Stroke and Poststroke Depression |
| title_short | Role of microRNAs in Stroke and Poststroke Depression |
| title_sort | role of micrornas in stroke and poststroke depression |
| url | http://dx.doi.org/10.1155/2013/459692 |
| work_keys_str_mv | AT hanyan roleofmicrornasinstrokeandpoststrokedepression AT minfang roleofmicrornasinstrokeandpoststrokedepression AT xueyuanliu roleofmicrornasinstrokeandpoststrokedepression |