Concurrent COVID-19 and Acute HIV: A Case Report and Diagnostic Review

A 26-year-old male presented to the emergency department feeling unwell in February of 2021 with symptoms including diaphoresis, loose stools, and loss of taste sensation. Workup not only confirmed a diagnosis of COVID-19 but also revealed discordant HIV test results, with a reactive fourth-generati...

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Main Authors: Kelly A. Johnson, Sally Graglia, Elizabeth D. Lynch, Joanna De Mesa, Erin Antunez, Sandra Torres, Susa Coffey, Stephanie E. Cohen
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2021/2653678
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author Kelly A. Johnson
Sally Graglia
Elizabeth D. Lynch
Joanna De Mesa
Erin Antunez
Sandra Torres
Susa Coffey
Stephanie E. Cohen
author_facet Kelly A. Johnson
Sally Graglia
Elizabeth D. Lynch
Joanna De Mesa
Erin Antunez
Sandra Torres
Susa Coffey
Stephanie E. Cohen
author_sort Kelly A. Johnson
collection DOAJ
description A 26-year-old male presented to the emergency department feeling unwell in February of 2021 with symptoms including diaphoresis, loose stools, and loss of taste sensation. Workup not only confirmed a diagnosis of COVID-19 but also revealed discordant HIV test results, with a reactive fourth-generation antigen/antibody test but a negative HIV-1/2 differentiation immunoassay. Subsequent HIV viral load testing obtained two days later ultimately established a diagnosis of acute HIV (AHI). Screening for HIV and other sexually transmitted infections decreased during the COVID-19 pandemic. It is critical that providers (1) continue recommended screening for HIV as an essential service; (2) consider acute HIV in the differential when evaluating patients with acute viral syndromes; (3) recognize that AHI can occur concurrently with other infections, including COVID-19; and (4) understand the differential diagnosis for discordant HIV test results and know when HIV viral load testing is needed to resolve such discordant results.
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spelling doaj-art-97309723daa84af99414d47bda1d69c22025-02-03T06:06:33ZengWileyCase Reports in Medicine1687-96352021-01-01202110.1155/2021/2653678Concurrent COVID-19 and Acute HIV: A Case Report and Diagnostic ReviewKelly A. Johnson0Sally Graglia1Elizabeth D. Lynch2Joanna De Mesa3Erin Antunez4Sandra Torres5Susa Coffey6Stephanie E. Cohen7University of California San FranciscoUniversity of California San FranciscoUniversity of California San FranciscoHealthRIGHT 360 ClinicSan Francisco Department of Public HealthUniversity of California San FranciscoUniversity of California San FranciscoUniversity of California San FranciscoA 26-year-old male presented to the emergency department feeling unwell in February of 2021 with symptoms including diaphoresis, loose stools, and loss of taste sensation. Workup not only confirmed a diagnosis of COVID-19 but also revealed discordant HIV test results, with a reactive fourth-generation antigen/antibody test but a negative HIV-1/2 differentiation immunoassay. Subsequent HIV viral load testing obtained two days later ultimately established a diagnosis of acute HIV (AHI). Screening for HIV and other sexually transmitted infections decreased during the COVID-19 pandemic. It is critical that providers (1) continue recommended screening for HIV as an essential service; (2) consider acute HIV in the differential when evaluating patients with acute viral syndromes; (3) recognize that AHI can occur concurrently with other infections, including COVID-19; and (4) understand the differential diagnosis for discordant HIV test results and know when HIV viral load testing is needed to resolve such discordant results.http://dx.doi.org/10.1155/2021/2653678
spellingShingle Kelly A. Johnson
Sally Graglia
Elizabeth D. Lynch
Joanna De Mesa
Erin Antunez
Sandra Torres
Susa Coffey
Stephanie E. Cohen
Concurrent COVID-19 and Acute HIV: A Case Report and Diagnostic Review
Case Reports in Medicine
title Concurrent COVID-19 and Acute HIV: A Case Report and Diagnostic Review
title_full Concurrent COVID-19 and Acute HIV: A Case Report and Diagnostic Review
title_fullStr Concurrent COVID-19 and Acute HIV: A Case Report and Diagnostic Review
title_full_unstemmed Concurrent COVID-19 and Acute HIV: A Case Report and Diagnostic Review
title_short Concurrent COVID-19 and Acute HIV: A Case Report and Diagnostic Review
title_sort concurrent covid 19 and acute hiv a case report and diagnostic review
url http://dx.doi.org/10.1155/2021/2653678
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