miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells

miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells

Although aberrant expression of miR-34a, an essential tumor suppressor miRNA, has been frequently observed in colon cancer (CCa), whether miR-34a can regulate CCa progression by modulating other facets of this malignancy (such as multidrug resistance, MDR) remains unknown. Here, we report for the fi...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yong Li, Ping Gong, Ji-xue Hou, Wei Huang, Xiao-ping Ma, Yu-li Wang, Jing Li, Xiao-bin Cui, Na Li
Format:	Article
Language:	English
Published:	Wiley 2018-01-01
Series:	Journal of Immunology Research
Online Access:	http://dx.doi.org/10.1155/2018/7498514
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Associations of miR-499 and miR-34b/c Polymorphisms with Susceptibility to Hepatocellular Carcinoma: An Evidence-Based Evaluation
by: Zhongxia Wang, et al.
Published: (2013-01-01)

The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells
by: Xiao Liang, et al.
Published: (2019-01-01)

Association of H-Type Hypertension with miR-21, miR-29, and miR-199 in Kazahks of Xinjiang, China
by: Xin He, et al.
Published: (2022-01-01)

Interactions of miR-34b/c and TP53 Polymorphisms on the Risk of Intracranial Aneurysm
by: Lijuan Li, et al.
Published: (2012-01-01)

TSC complex decrease the expression of mTOR by regulated miR-199b-3p
by: Na Zhao, et al.
Published: (2025-01-01)

Liraglutide Regulates the Kidney and Liver in Diabetic Nephropathy Rats through the miR-34a/SIRT1 Pathway
by: Shan Xiao, et al.
Published: (2021-01-01)

Downregulation of Bcl-2 Expression by miR-34a Mediates Palmitate-Induced Min6 Cells Apoptosis
by: Xiaojie Lin, et al.
Published: (2014-01-01)

Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis
by: Ferah Budak, et al.
Published: (2016-01-01)

miR-126 and miR-126*: New Players in Cancer
by: Jeannette Meister, et al.
Published: (2010-01-01)

Elevated Circulating hsa-miR-106b, hsa-miR-26a, and hsa-miR-29b in Type 2 Diabetes Mellitus with Diarrhea-Predominant Irritable Bowel Syndrome
by: Wenhua Tao, et al.
Published: (2016-01-01)

Biochemical analysis of miR-217 and miR-532 in patients with fibromyalgia
by: Shymaa E. Ayoub, et al.
Published: (2025-02-01)

Exosome miR-199a-5p modulated vascular remodeling and inflammatory infiltration of Takayasu’s arteritis
by: Shuning Guo, et al.
Published: (2025-01-01)

Electroacupuncture alleviates functional constipation by upregulating host-derived miR-205-5p to modulate gut microbiota and tryptophan metabolism
by: Lu Wang, et al.
Published: (2025-02-01)

The Expression of miR-34a in Gingival Crevicular Fluid of Chronic Periodontitis and Its Connection with the TLR/NF-κB Signaling Pathway
by: Jiaxin Pan, et al.
Published: (2022-01-01)

LINC00707 Regulates miR-382-5p/VEGFA Pathway to Enhance Cervical Cancer Progression
by: Hua Guo, et al.
Published: (2021-01-01)

Metformin Regulating miR-34a Pathway to Inhibit Egr1 in Rat Mesangial Cells Cultured with High Glucose
by: Can Wu, et al.
Published: (2018-01-01)

Retracted: The Expression of miR-34a in Gingival Crevicular Fluid of Chronic Periodontitis and Its Connection with the TLR/NF-κB Signaling Pathway
by: Applied Bionics and Biomechanics
Published: (2023-01-01)

circ_0001588 Induces the Malignant Progression of Hepatocellular Carcinoma by Modulating miR-874/CDK4 Signaling
by: Xiaoyun Bin, et al.
Published: (2021-01-01)

miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1
by: Miaomiao Liu, et al.
Published: (2022-01-01)

Spatiotemporal Expression and Molecular Characterization of miR-344b and miR-344c in the Developing Mouse Brain
by: Jia-Wen Leong, et al.
Published: (2016-01-01)

Hsa_circ_0000190 Promotes NSCLC Cell Resistance to Cisplatin via the Modulation of the miR-1253/IL-6 Axis
by: Hua He, et al.
Published: (2024-01-01)

circHUWE1 Exerts an Oncogenic Role in Inducing DDP-Resistant NSCLC Progression Depending on the Regulation of miR-34a-5p/TNFAIP8
by: Xueliang Yang, et al.
Published: (2021-01-01)

Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p
by: Lu Wang, et al.
Published: (2021-01-01)

Reduced Circulating Levels of miR-491-5p and miR-485-3p Are Associated with the Occurrence of Vertebral Fractures in Postmenopausal Women with Osteoporosis
by: Jixi Xu, et al.
Published: (2022-01-01)

Elevated and Correlated Expressions of miR-24, miR-30d, miR-146a, and SFRP-4 in Human Abdominal Adipose Tissue Play a Role in Adiposity and Insulin Resistance
by: Yury O. Nunez Lopez, et al.
Published: (2018-01-01)

The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow
by: Sirikul Manochantr, et al.
Published: (2017-01-01)

circRNA_101277 Influences Cisplatin Resistance of Colorectal Cancer Cells by Modulating the miR-370/IL-6 Axis
by: Qing Lv, et al.
Published: (2022-01-01)

Dihydromyricetin Inhibits M1 Macrophage Polarization in Atherosclerosis by Modulating miR-9-Mediated SIRT1/NF-κB Signaling Pathway
by: Zhousheng Yang, et al.
Published: (2023-01-01)

Astrocyte-derived exosomes regulate sperm miR-34c levels to mediate the transgenerational effects of paternal chronic social instability stress
by: Alexandre Champroux, et al.
Published: (2025-12-01)

CircBAZ1B stimulates myocardial ischemia/reperfusion injury (MI/RI) by modulating miR-1252-5p/ATF3-mediated ferroptosis
by: Ruili Wei, et al.
Published: (2024-05-01)

Circular RNA ITCH Is a Tumor Suppressor in Clear Cell Renal Cell Carcinoma Metastasis through miR-106b-5p/PDCD4 Axis
by: Ping Gao, et al.
Published: (2021-01-01)

Bifurcations and Dynamics of the Rb-E2F Pathway Involving miR449
by: Lingling Li, et al.
Published: (2017-01-01)

Caesalpinia sappan L. ethyl acetate extract regulated angiogenesis in atherosclerosis by modulating the miR-126/VEGF signalling pathway
by: Yue He, et al.
Published: (2025-02-01)

MiR-9-z/zp2, miR-3154-y/zp2, and miR-3533-y/zp3 participated in ovarian development and adaptation to salinity stress in spotted scat (Scatophagus argus)
by: Zhuoying Leng, et al.
Published: (2025-03-01)

miR-155: An Important Role in Inflammation Response
by: Jingyan Hu, et al.
Published: (2022-01-01)

miR-224-5p Attenuates Allergic Responses in Mice with Allergic Rhinitis by Modulating the Th1/Th2 Response
by: Yuxiao Li, et al.
Published: (2024-01-01)

miR-146a expression and the miR-146a gene variant rs2910164 as diagnostic and prognostic biomarkers of oral cancer
by: Vuković Miodrag, et al.
Published: (2024-01-01)

Inhibition of miR-182-5p Targets FGF9 to Alleviate Osteoarthritis
by: Yang Sun, et al.
Published: (2023-01-01)

Exosomes Derived from Apelin-Pretreated Mesenchymal Stem Cells Ameliorate Sepsis-Induced Myocardial Dysfunction by Alleviating Cardiomyocyte Pyroptosis via Delivery of miR-34a-5p
by: Li T, et al.
Published: (2025-01-01)

miR-129-5p Regulates the Immunomodulatory Functions of Adipose-Derived Stem Cells via Targeting Stat1 Signaling
by: He-Yang Zhang, et al.
Published: (2019-01-01)