7,12-Dimethylbenz(a)anthracene as a Model for Ovarian Cancer Induction in Rats

7,12-Dimethylbenz(a)anthracene as a Model for Ovarian Cancer Induction in Rats

Ovarian cancer has the highest mortality rate of all gynecological cancers. Animal models using 7,12-dimethylbenz(a)anthracene (DMBA) have been developed to investigate the mechanisms of ovarian carcinogenesis. The present study is a systematic review of efforts to establish DMBA as a model for ovar...

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Bibliographic Details
Main Authors: Ana Carolina Ciseski Gonçalves, Katia Candido Carvalho, José Antônio Orellana Turri, Ricardo dos Santos Simões, Jesus Paula Carvalho, Luiz Fernando Ferraz da Silva, José Maria Soares Júnior, Edmund Chada Baracat
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biology
Subjects:
ovarian cancer
DMBA
animal model
Online Access:https://www.mdpi.com/2079-7737/14/1/73
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