Effects of Anesthetics on Barrier Tissue Function

Anesthetics have long been proven to have additional effects other than anesthesia on different organs and tissues of the human body. Barrier tissues play critical roles in human health and diseases, yet the impacts of anesthetics on barrier tissues are still not clear. This review article is aimed...

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Main Authors: Fujing Wang, Yanhui Li, Changlei Cui, Zhaoping Xue, Haichun Ma
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/5920620
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author Fujing Wang
Yanhui Li
Changlei Cui
Zhaoping Xue
Haichun Ma
author_facet Fujing Wang
Yanhui Li
Changlei Cui
Zhaoping Xue
Haichun Ma
author_sort Fujing Wang
collection DOAJ
description Anesthetics have long been proven to have additional effects other than anesthesia on different organs and tissues of the human body. Barrier tissues play critical roles in human health and diseases, yet the impacts of anesthetics on barrier tissues are still not clear. This review article is aimed at summarizing different effects of anesthetics on the skin, the respiratory, and intestinal membranes from two aspects: inflammation/immunity and ischemia-reperfusion. Among volatile, intravenous, and local anesthetics, volatile anesthetics are less influential on barrier ischemia-perfusion function. Although direct comparisons between volatile and the other two types of anesthetics are still lacking, volatile anesthetics appear to have stronger anti-inflammatory effects on different barrier tissues through various mechanisms. These results suggested that when treating patients with barrier tissue complications, volatile anesthetics can provide better therapeutic outcomes.
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publishDate 2019-01-01
publisher Wiley
record_format Article
series Journal of Immunology Research
spelling doaj-art-96a33c366d264f91af14f4885b021ba52025-02-03T06:08:10ZengWileyJournal of Immunology Research2314-88612314-71562019-01-01201910.1155/2019/59206205920620Effects of Anesthetics on Barrier Tissue FunctionFujing Wang0Yanhui Li1Changlei Cui2Zhaoping Xue3Haichun Ma4Department of Anesthesia, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, Jilin Province 130021, ChinaDepartment of Anesthesia, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, Jilin Province 130021, ChinaDepartment of Anesthesia, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, Jilin Province 130021, ChinaPostanesthesia Care Unit, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, Jilin Province 130021, ChinaDepartment of Anesthesia, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, Jilin Province 130021, ChinaAnesthetics have long been proven to have additional effects other than anesthesia on different organs and tissues of the human body. Barrier tissues play critical roles in human health and diseases, yet the impacts of anesthetics on barrier tissues are still not clear. This review article is aimed at summarizing different effects of anesthetics on the skin, the respiratory, and intestinal membranes from two aspects: inflammation/immunity and ischemia-reperfusion. Among volatile, intravenous, and local anesthetics, volatile anesthetics are less influential on barrier ischemia-perfusion function. Although direct comparisons between volatile and the other two types of anesthetics are still lacking, volatile anesthetics appear to have stronger anti-inflammatory effects on different barrier tissues through various mechanisms. These results suggested that when treating patients with barrier tissue complications, volatile anesthetics can provide better therapeutic outcomes.http://dx.doi.org/10.1155/2019/5920620
spellingShingle Fujing Wang
Yanhui Li
Changlei Cui
Zhaoping Xue
Haichun Ma
Effects of Anesthetics on Barrier Tissue Function
Journal of Immunology Research
title Effects of Anesthetics on Barrier Tissue Function
title_full Effects of Anesthetics on Barrier Tissue Function
title_fullStr Effects of Anesthetics on Barrier Tissue Function
title_full_unstemmed Effects of Anesthetics on Barrier Tissue Function
title_short Effects of Anesthetics on Barrier Tissue Function
title_sort effects of anesthetics on barrier tissue function
url http://dx.doi.org/10.1155/2019/5920620
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