Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

Abstract Toxoplasma gondii is an important food and waterborne pathogen causing toxoplasmosis, a potentially severe disease in immunocompromised or congenitally infected humans. Available therapeutic agents are limited by suboptimal efficacy and frequent side effects that can lead to treatment disco...

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Main Authors: Andrés Palencia, Alexandre Bougdour, Marie‐Pierre Brenier‐Pinchart, Bastien Touquet, Rose‐Laurence Bertini, Cristina Sensi, Gabrielle Gay, Julien Vollaire, Véronique Josserand, Eric Easom, Yvonne R Freund, Hervé Pelloux, Philip J Rosenthal, Stephen Cusack, Mohamed‐Ali Hakimi
Format: Article
Language:English
Published: Springer Nature 2017-02-01
Series:EMBO Molecular Medicine
Subjects:
benzoxaborole
CPSF3
drug discovery
mRNA processing
Toxoplasma gondii
toxoplasmosis
Online Access:https://doi.org/10.15252/emmm.201607370
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