Acute Painful Transfusion Reactions (APTRs): A Comprehensive Review of Clinical Features, Pathophysiology, Diagnosis, and Management
It is important to recognize the significance of acute painful transfusion reactions (APTRs) as a complication of blood transfusions. These adverse reactions are characterized by the onset of acute pain after the administration of blood components. Despite their potential to cause significant discom...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Thalassemia Reports |
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| Online Access: | https://www.mdpi.com/2039-4365/15/1/1 |
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| author | Sophia Delicou Aspasia Argyrou Sophia Mellou Aikaterini Xydaki Anthippi Gafou Constantina Politis |
| author_facet | Sophia Delicou Aspasia Argyrou Sophia Mellou Aikaterini Xydaki Anthippi Gafou Constantina Politis |
| author_sort | Sophia Delicou |
| collection | DOAJ |
| description | It is important to recognize the significance of acute painful transfusion reactions (APTRs) as a complication of blood transfusions. These adverse reactions are characterized by the onset of acute pain after the administration of blood components. Despite their potential to cause significant discomfort and distress to patients, these reactions are frequently disregarded and under-reported in clinical practice. This review aims to provide a comprehensive analysis of the clinical features, pathophysiology, diagnosis, incidence, and management of APTRs, emphasizing the necessity for heightened awareness and further research in this field. |
| format | Article |
| id | doaj-art-965d12a3fa0e476491804787ce692eb5 |
| institution | DOAJ |
| issn | 2039-4365 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Thalassemia Reports |
| spelling | doaj-art-965d12a3fa0e476491804787ce692eb52025-08-20T02:43:04ZengMDPI AGThalassemia Reports2039-43652025-01-01151110.3390/thalassrep15010001Acute Painful Transfusion Reactions (APTRs): A Comprehensive Review of Clinical Features, Pathophysiology, Diagnosis, and ManagementSophia Delicou0Aspasia Argyrou1Sophia Mellou2Aikaterini Xydaki3Anthippi Gafou4Constantina Politis5Thalassemia and Sickle Cell Unit, Expertise Center of Hemoglobinopathies and Their Complications, Hippocration General Hospital, GR-11527 Athens, GreeceDepartment of Blood Transfusion, “Agioi Anargyroi” Hospital, 14564 Athens, GreeceTransfusion Department, General Hospital of Athens “G. Gennimatas”, 11527 Athens, GreeceThalassemia and Sickle Cell Unit, Expertise Center of Hemoglobinopathies and Their Complications, Hippocration General Hospital, GR-11527 Athens, GreeceDepartment of Blood Transfusion, “Agioi Anargyroi” Hospital, 14564 Athens, GreeceCoordinating Haemovigilance Centre and Surveillance of Transfusion, Hellenic National Public Health Organisation, EL-15123 Athens, GreeceIt is important to recognize the significance of acute painful transfusion reactions (APTRs) as a complication of blood transfusions. These adverse reactions are characterized by the onset of acute pain after the administration of blood components. Despite their potential to cause significant discomfort and distress to patients, these reactions are frequently disregarded and under-reported in clinical practice. This review aims to provide a comprehensive analysis of the clinical features, pathophysiology, diagnosis, incidence, and management of APTRs, emphasizing the necessity for heightened awareness and further research in this field.https://www.mdpi.com/2039-4365/15/1/1blood transfusion complicationshemovigilancetransfusion safety |
| spellingShingle | Sophia Delicou Aspasia Argyrou Sophia Mellou Aikaterini Xydaki Anthippi Gafou Constantina Politis Acute Painful Transfusion Reactions (APTRs): A Comprehensive Review of Clinical Features, Pathophysiology, Diagnosis, and Management Thalassemia Reports blood transfusion complications hemovigilance transfusion safety |
| title | Acute Painful Transfusion Reactions (APTRs): A Comprehensive Review of Clinical Features, Pathophysiology, Diagnosis, and Management |
| title_full | Acute Painful Transfusion Reactions (APTRs): A Comprehensive Review of Clinical Features, Pathophysiology, Diagnosis, and Management |
| title_fullStr | Acute Painful Transfusion Reactions (APTRs): A Comprehensive Review of Clinical Features, Pathophysiology, Diagnosis, and Management |
| title_full_unstemmed | Acute Painful Transfusion Reactions (APTRs): A Comprehensive Review of Clinical Features, Pathophysiology, Diagnosis, and Management |
| title_short | Acute Painful Transfusion Reactions (APTRs): A Comprehensive Review of Clinical Features, Pathophysiology, Diagnosis, and Management |
| title_sort | acute painful transfusion reactions aptrs a comprehensive review of clinical features pathophysiology diagnosis and management |
| topic | blood transfusion complications hemovigilance transfusion safety |
| url | https://www.mdpi.com/2039-4365/15/1/1 |
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