Metabolic plasticity in pancreatic cancer: The mitochondrial connection

Metabolic plasticity in pancreatic cancer: The mitochondrial connection

Background: Cellular metabolism plays a pivotal role in the development and progression of pancreatic ductal adenocarcinoma (PDAC), with dysregulated metabolic pathways contributing to tumorigenesis and therapeutic resistance. Distinct metabolic heterogeneity in pancreatic cancer significantly impac...

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Bibliographic Details
Main Authors: Noemi Ghiglione, Damiano Abbo, Anastasia Bushunova, Andrea Costamagna, Paolo Ettore Porporato, Miriam Martini
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Molecular Metabolism
Subjects:
Pancreatic cancer
Mitochondria
Metabolism
Oxidative phosphorylation
Mitophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824002205
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