Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be success...
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Wiley
2012-01-01
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Series: | Case Reports in Critical Care |
Online Access: | http://dx.doi.org/10.1155/2012/295867 |
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author | Qi Jin Erzhen Chen Jie Jiang Yiming Lu |
author_facet | Qi Jin Erzhen Chen Jie Jiang Yiming Lu |
author_sort | Qi Jin |
collection | DOAJ |
description | Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be successful in treating heat-stroke-associated AHF even in the presence of accepted criteria for emergency liver transplantation. Case Presentation. Here, we reported a 35-year-old male who presented with very high transaminases, hyperbilirubinemia, significant prolongation of the prothrombin time, and coma. No other causes for AHF could be identified but physical exhaustion and hyperthermia. Although the current patient fulfilled London criteria for emergency liver transplantation, he spontaneously recovered under conservative treatment including intravenous fluids, cooling, diuretics as mannitol, and hepatocyte growth-promoting factors. Conclusions. Meticulous supportive management could be justified in some selected cases of AHF due to EHS. |
format | Article |
id | doaj-art-9637e4a07e2147ff821c5153525d2d67 |
institution | Kabale University |
issn | 2090-6420 2090-6439 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Critical Care |
spelling | doaj-art-9637e4a07e2147ff821c5153525d2d672025-02-03T06:00:46ZengWileyCase Reports in Critical Care2090-64202090-64392012-01-01201210.1155/2012/295867295867Acute Hepatic Failure as a Leading Manifestation in Exertional Heat StrokeQi Jin0Erzhen Chen1Jie Jiang2Yiming Lu3Department of Emergency, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, ChinaDepartment of Emergency, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, ChinaDepartment of Emergency, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, ChinaDepartment of Emergency, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, ChinaBackground. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be successful in treating heat-stroke-associated AHF even in the presence of accepted criteria for emergency liver transplantation. Case Presentation. Here, we reported a 35-year-old male who presented with very high transaminases, hyperbilirubinemia, significant prolongation of the prothrombin time, and coma. No other causes for AHF could be identified but physical exhaustion and hyperthermia. Although the current patient fulfilled London criteria for emergency liver transplantation, he spontaneously recovered under conservative treatment including intravenous fluids, cooling, diuretics as mannitol, and hepatocyte growth-promoting factors. Conclusions. Meticulous supportive management could be justified in some selected cases of AHF due to EHS.http://dx.doi.org/10.1155/2012/295867 |
spellingShingle | Qi Jin Erzhen Chen Jie Jiang Yiming Lu Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke Case Reports in Critical Care |
title | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_full | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_fullStr | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_full_unstemmed | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_short | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_sort | acute hepatic failure as a leading manifestation in exertional heat stroke |
url | http://dx.doi.org/10.1155/2012/295867 |
work_keys_str_mv | AT qijin acutehepaticfailureasaleadingmanifestationinexertionalheatstroke AT erzhenchen acutehepaticfailureasaleadingmanifestationinexertionalheatstroke AT jiejiang acutehepaticfailureasaleadingmanifestationinexertionalheatstroke AT yiminglu acutehepaticfailureasaleadingmanifestationinexertionalheatstroke |