Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke

Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be success...

Full description

Saved in:
Bibliographic Details
Main Authors: Qi Jin, Erzhen Chen, Jie Jiang, Yiming Lu
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2012/295867
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832551688820490240
author Qi Jin
Erzhen Chen
Jie Jiang
Yiming Lu
author_facet Qi Jin
Erzhen Chen
Jie Jiang
Yiming Lu
author_sort Qi Jin
collection DOAJ
description Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be successful in treating heat-stroke-associated AHF even in the presence of accepted criteria for emergency liver transplantation. Case Presentation. Here, we reported a 35-year-old male who presented with very high transaminases, hyperbilirubinemia, significant prolongation of the prothrombin time, and coma. No other causes for AHF could be identified but physical exhaustion and hyperthermia. Although the current patient fulfilled London criteria for emergency liver transplantation, he spontaneously recovered under conservative treatment including intravenous fluids, cooling, diuretics as mannitol, and hepatocyte growth-promoting factors. Conclusions. Meticulous supportive management could be justified in some selected cases of AHF due to EHS.
format Article
id doaj-art-9637e4a07e2147ff821c5153525d2d67
institution Kabale University
issn 2090-6420
2090-6439
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Case Reports in Critical Care
spelling doaj-art-9637e4a07e2147ff821c5153525d2d672025-02-03T06:00:46ZengWileyCase Reports in Critical Care2090-64202090-64392012-01-01201210.1155/2012/295867295867Acute Hepatic Failure as a Leading Manifestation in Exertional Heat StrokeQi Jin0Erzhen Chen1Jie Jiang2Yiming Lu3Department of Emergency, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, ChinaDepartment of Emergency, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, ChinaDepartment of Emergency, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, ChinaDepartment of Emergency, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, ChinaBackground. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be successful in treating heat-stroke-associated AHF even in the presence of accepted criteria for emergency liver transplantation. Case Presentation. Here, we reported a 35-year-old male who presented with very high transaminases, hyperbilirubinemia, significant prolongation of the prothrombin time, and coma. No other causes for AHF could be identified but physical exhaustion and hyperthermia. Although the current patient fulfilled London criteria for emergency liver transplantation, he spontaneously recovered under conservative treatment including intravenous fluids, cooling, diuretics as mannitol, and hepatocyte growth-promoting factors. Conclusions. Meticulous supportive management could be justified in some selected cases of AHF due to EHS.http://dx.doi.org/10.1155/2012/295867
spellingShingle Qi Jin
Erzhen Chen
Jie Jiang
Yiming Lu
Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
Case Reports in Critical Care
title Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_full Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_fullStr Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_full_unstemmed Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_short Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_sort acute hepatic failure as a leading manifestation in exertional heat stroke
url http://dx.doi.org/10.1155/2012/295867
work_keys_str_mv AT qijin acutehepaticfailureasaleadingmanifestationinexertionalheatstroke
AT erzhenchen acutehepaticfailureasaleadingmanifestationinexertionalheatstroke
AT jiejiang acutehepaticfailureasaleadingmanifestationinexertionalheatstroke
AT yiminglu acutehepaticfailureasaleadingmanifestationinexertionalheatstroke