Orbital ameloblastoma: research and challenges of a rare benign tumor

Abstract There are numerous types of orbital tumors, among which orbital ameloblastoma is a rare metastatic benign tumor that often originates in the jaw and later metastasizes to the orbit. The mystery of it lies in that, although it is classified as a benign tumor, it exhibits high recurrence and...

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Main Authors: Rui Zhang, Xiaoming Huang, Fengyuan Sun, Tong Wu
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Holistic Integrative Oncology
Subjects:
Online Access:https://doi.org/10.1007/s44178-024-00145-1
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author Rui Zhang
Xiaoming Huang
Fengyuan Sun
Tong Wu
author_facet Rui Zhang
Xiaoming Huang
Fengyuan Sun
Tong Wu
author_sort Rui Zhang
collection DOAJ
description Abstract There are numerous types of orbital tumors, among which orbital ameloblastoma is a rare metastatic benign tumor that often originates in the jaw and later metastasizes to the orbit. The mystery of it lies in that, although it is classified as a benign tumor, it exhibits high recurrence and malignant potential with high invasiveness, posing a serious threat to ocular health and the quality of life of patients. The prognosis of orbital ameloblastoma is relatively poor, but there is still hope. With aggressive treatment and close follow-up observation, patients may still have the possibility of achieving a longer survival period and a better quality of life. The global incidence of ameloblastoma is 0.92 cases per million people per year. According to world literature reports, there are 32 cases of maxillary bone metastasis to the orbit and 4 cases of mandibular bone metastasis to the orbit. With more and more cases and related research being reported, it is necessary to comprehensively review the etiology, clinical manifestations, diagnosis, treatment, and prognosis of orbital ameloblastoma, in order to enhance ophthalmologists' understanding and diagnostic and treatment skills of this disease, and ultimately improve patients' prognosis and quality of life.
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spelling doaj-art-9608c982a6304b51bd1032431f6fa4582025-01-19T12:43:04ZengSpringerHolistic Integrative Oncology2731-45292025-01-01411610.1007/s44178-024-00145-1Orbital ameloblastoma: research and challenges of a rare benign tumorRui Zhang0Xiaoming Huang1Fengyuan Sun2Tong Wu3Department of Orbital Disease and Oculoplastic Surgery, Aier Eye Hospital (East of Chengdu), AIER Eye Hospital GroupDepartment of Orbital Disease and Oculoplastic Surgery, Sichuan Eye Hospital, AIER Eye Hospital GroupDepartment of Orbital Disease and Oculoplastic Surgery, Sichuan Eye Hospital, AIER Eye Hospital GroupDepartment of Orbital Disease and Oculoplastic Surgery, Sichuan Eye Hospital, AIER Eye Hospital GroupAbstract There are numerous types of orbital tumors, among which orbital ameloblastoma is a rare metastatic benign tumor that often originates in the jaw and later metastasizes to the orbit. The mystery of it lies in that, although it is classified as a benign tumor, it exhibits high recurrence and malignant potential with high invasiveness, posing a serious threat to ocular health and the quality of life of patients. The prognosis of orbital ameloblastoma is relatively poor, but there is still hope. With aggressive treatment and close follow-up observation, patients may still have the possibility of achieving a longer survival period and a better quality of life. The global incidence of ameloblastoma is 0.92 cases per million people per year. According to world literature reports, there are 32 cases of maxillary bone metastasis to the orbit and 4 cases of mandibular bone metastasis to the orbit. With more and more cases and related research being reported, it is necessary to comprehensively review the etiology, clinical manifestations, diagnosis, treatment, and prognosis of orbital ameloblastoma, in order to enhance ophthalmologists' understanding and diagnostic and treatment skills of this disease, and ultimately improve patients' prognosis and quality of life.https://doi.org/10.1007/s44178-024-00145-1AmeloblastomaOrbital tumorsMetastasesReview
spellingShingle Rui Zhang
Xiaoming Huang
Fengyuan Sun
Tong Wu
Orbital ameloblastoma: research and challenges of a rare benign tumor
Holistic Integrative Oncology
Ameloblastoma
Orbital tumors
Metastases
Review
title Orbital ameloblastoma: research and challenges of a rare benign tumor
title_full Orbital ameloblastoma: research and challenges of a rare benign tumor
title_fullStr Orbital ameloblastoma: research and challenges of a rare benign tumor
title_full_unstemmed Orbital ameloblastoma: research and challenges of a rare benign tumor
title_short Orbital ameloblastoma: research and challenges of a rare benign tumor
title_sort orbital ameloblastoma research and challenges of a rare benign tumor
topic Ameloblastoma
Orbital tumors
Metastases
Review
url https://doi.org/10.1007/s44178-024-00145-1
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AT xiaominghuang orbitalameloblastomaresearchandchallengesofararebenigntumor
AT fengyuansun orbitalameloblastomaresearchandchallengesofararebenigntumor
AT tongwu orbitalameloblastomaresearchandchallengesofararebenigntumor