Effect of Study-Duration and Time of Day on Multichannel Sleep Study Findings in Former Preterm Infants

Background/Objectives: Determine the appropriate duration for multichannel sleep studies in former preterm infants with cardio-respiratory events beyond term equivalent age. Hypothesis: A sleep study of 10 h will provide equivalent information compared to a 20-h study to detect significant cardio-re...

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Bibliographic Details
Main Authors: Allison Sadowski, Naveed Hussain, Leonard I. Eisenfeld, Mariann Pappagallo, Janet Schwenn, Ted S. Rosenkrantz
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Children
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Online Access:https://www.mdpi.com/2227-9067/12/1/74
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Summary:Background/Objectives: Determine the appropriate duration for multichannel sleep studies in former preterm infants with cardio-respiratory events beyond term equivalent age. Hypothesis: A sleep study of 10 h will provide equivalent information compared to a 20-h study to detect significant cardio-respiratory abnormalities in this population. Methods: Single-center retrospective study of 50 infants with 20-h sleep study. Studies were evaluated for periodic breathing, obstructive, central, mixed apnea, desaturations, and bradycardia. Each study was partitioned into two 10-h epochs, compared to one another and the 20-h study. Results: Differences were detected at the level of individual sleep studies when each epoch was compared to each other and a total 20-h study. 10-h study missed 17–31% of breathing abnormalities detected over 20 h adjusted for study time. Group analysis showed no statistical difference in the number and duration of events between epochs. Conclusions: A 20-h sleep study improves the detection of breathing abnormalities missed with a 10-h study.
ISSN:2227-9067