A comprehensive map of the mTOR signaling network
Abstract The mammalian target of rapamycin (mTOR) is a central regulator of cell growth and proliferation. mTOR signaling is frequently dysregulated in oncogenic cells, and thus an attractive target for anticancer therapy. Using CellDesigner, a modeling support software for graphical notation, we pr...
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| Main Authors: | Etienne Caron, Samik Ghosh, Yukiko Matsuoka, Dariel Ashton‐Beaucage, Marc Therrien, Sébastien Lemieux, Claude Perreault, Philippe P Roux, Hiroaki Kitano |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2010-12-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb.2010.108 |
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