Dermoscopic and Histopathological Association in Pyogenic Granuloma: A Case Series in Skin of Color

Introduction: Pyogenic granuloma (PG) is a common benign vascular lesion, presenting as a rapidly growing papule or polyp that bleeds easily. Diagnosing PG can be challenging due to its clinical similarity to other tumors. Dermoscopy offers improved accuracy in identifying such vascular by demonstra...

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Main Authors: Balachandra Suryakant Ankad, Anirudh A Mallapur, Sahana S Hurakadli
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Clinical Dermatology Review
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Online Access:https://journals.lww.com/10.4103/cdr.cdr_77_24
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author Balachandra Suryakant Ankad
Anirudh A Mallapur
Sahana S Hurakadli
author_facet Balachandra Suryakant Ankad
Anirudh A Mallapur
Sahana S Hurakadli
author_sort Balachandra Suryakant Ankad
collection DOAJ
description Introduction: Pyogenic granuloma (PG) is a common benign vascular lesion, presenting as a rapidly growing papule or polyp that bleeds easily. Diagnosing PG can be challenging due to its clinical similarity to other tumors. Dermoscopy offers improved accuracy in identifying such vascular by demonstrating features. This study aims to explore dermoscopic features with their association to histopathological changes in PG in skin of color. Materials and Methods: A prospective observational case series study was conducted at S. Nijalingappa Medical College from January 2022 to November 2022. Patients with clinical signs of PG were included, while those with infected and oozing lesions were excluded. Demographic data, clinical evaluation, photographic documentation, dermoscopic examination, and histopathological analysis were performed. Statistical analysis was carried out using SPSS Statistics v20.0. Results: A total of 30 patients (13 males, 17 females) were included. Solitary red papule on face and scalp was common presentation. Dermoscopic features included reddish homogeneous areas (96.7%), white collarette (80%), white linear rail-lines (60%), hemorrhagic crust (30%), and rainbow phenomenon (30%). Dotted, linear irregular, and hairpin vessels were vascular patterns. Histopathology showed dilated blood vessels in a lobular arrangement (96.7%), hyperplastic epithelium forming a collarette (73.3%), and collagen bundles (56.7%). Statistically significant correlation was found in reddish homogeneous areas (P=0.001) white collarette (P=0.005) and white rail lines(P=0.001) with corresponding histopathological changes. Conclusion: Dermoscopy identifies characteristic features in PG effectively, aiding differentiation from similar lesions. The association with histopathological changes validates its diagnostic and monitoring relevance. Further studies with larger sample sizes are recommended.
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spelling doaj-art-957fec2685994bfcaccdb5cf3fc24c4e2025-02-06T05:07:41ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282025-01-0191353910.4103/cdr.cdr_77_24Dermoscopic and Histopathological Association in Pyogenic Granuloma: A Case Series in Skin of ColorBalachandra Suryakant AnkadAnirudh A MallapurSahana S HurakadliIntroduction: Pyogenic granuloma (PG) is a common benign vascular lesion, presenting as a rapidly growing papule or polyp that bleeds easily. Diagnosing PG can be challenging due to its clinical similarity to other tumors. Dermoscopy offers improved accuracy in identifying such vascular by demonstrating features. This study aims to explore dermoscopic features with their association to histopathological changes in PG in skin of color. Materials and Methods: A prospective observational case series study was conducted at S. Nijalingappa Medical College from January 2022 to November 2022. Patients with clinical signs of PG were included, while those with infected and oozing lesions were excluded. Demographic data, clinical evaluation, photographic documentation, dermoscopic examination, and histopathological analysis were performed. Statistical analysis was carried out using SPSS Statistics v20.0. Results: A total of 30 patients (13 males, 17 females) were included. Solitary red papule on face and scalp was common presentation. Dermoscopic features included reddish homogeneous areas (96.7%), white collarette (80%), white linear rail-lines (60%), hemorrhagic crust (30%), and rainbow phenomenon (30%). Dotted, linear irregular, and hairpin vessels were vascular patterns. Histopathology showed dilated blood vessels in a lobular arrangement (96.7%), hyperplastic epithelium forming a collarette (73.3%), and collagen bundles (56.7%). Statistically significant correlation was found in reddish homogeneous areas (P=0.001) white collarette (P=0.005) and white rail lines(P=0.001) with corresponding histopathological changes. Conclusion: Dermoscopy identifies characteristic features in PG effectively, aiding differentiation from similar lesions. The association with histopathological changes validates its diagnostic and monitoring relevance. Further studies with larger sample sizes are recommended.https://journals.lww.com/10.4103/cdr.cdr_77_24dermoscopyhistopathologypyogenic granulomarainbow phenomenonvascular growth
spellingShingle Balachandra Suryakant Ankad
Anirudh A Mallapur
Sahana S Hurakadli
Dermoscopic and Histopathological Association in Pyogenic Granuloma: A Case Series in Skin of Color
Clinical Dermatology Review
dermoscopy
histopathology
pyogenic granuloma
rainbow phenomenon
vascular growth
title Dermoscopic and Histopathological Association in Pyogenic Granuloma: A Case Series in Skin of Color
title_full Dermoscopic and Histopathological Association in Pyogenic Granuloma: A Case Series in Skin of Color
title_fullStr Dermoscopic and Histopathological Association in Pyogenic Granuloma: A Case Series in Skin of Color
title_full_unstemmed Dermoscopic and Histopathological Association in Pyogenic Granuloma: A Case Series in Skin of Color
title_short Dermoscopic and Histopathological Association in Pyogenic Granuloma: A Case Series in Skin of Color
title_sort dermoscopic and histopathological association in pyogenic granuloma a case series in skin of color
topic dermoscopy
histopathology
pyogenic granuloma
rainbow phenomenon
vascular growth
url https://journals.lww.com/10.4103/cdr.cdr_77_24
work_keys_str_mv AT balachandrasuryakantankad dermoscopicandhistopathologicalassociationinpyogenicgranulomaacaseseriesinskinofcolor
AT anirudhamallapur dermoscopicandhistopathologicalassociationinpyogenicgranulomaacaseseriesinskinofcolor
AT sahanashurakadli dermoscopicandhistopathologicalassociationinpyogenicgranulomaacaseseriesinskinofcolor