DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDS
A panel of 96 DNA samples that reflects the breadth of genetic diversity in popular Russian cattle breeds has been designed. The panel of cattle DNA contains 11 dairy breeds and 6 beef and beef-dairy breeds. The numbers of animals in each breed group vary from 4 to 8. The main criterion for selectio...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2015-01-01
|
| Series: | Вавиловский журнал генетики и селекции |
| Subjects: | |
| Online Access: | https://vavilov.elpub.ru/jour/article/view/270 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832575315508985856 |
|---|---|
| author | N. S. Yudin L. A. Vasil’eva V. A. Belyavskaya R. B. Aitnazarov P. N. Smirnov M. Heaton W. W. Laegreid G. V. Orlova A. G. Romashchenko M. I. Voevoda |
| author_facet | N. S. Yudin L. A. Vasil’eva V. A. Belyavskaya R. B. Aitnazarov P. N. Smirnov M. Heaton W. W. Laegreid G. V. Orlova A. G. Romashchenko M. I. Voevoda |
| author_sort | N. S. Yudin |
| collection | DOAJ |
| description | A panel of 96 DNA samples that reflects the breadth of genetic diversity in popular Russian cattle breeds has been designed. The panel of cattle DNA contains 11 dairy breeds and 6 beef and beef-dairy breeds. The numbers of animals in each breed group vary from 4 to 8. The main criterion for selection of individual animals within each breed is to maximize the total number of unshared haploid genomes according to pedigree data. The resulting panel is equivalent to USDA MARC Beef Cattle Diversity Panel version 2.1 in the power of SNP identification (number of unshared haploid genomes = 186,1, minimum allele frequency required for its detection with 95 % probability – 1,6 %). Analysis of three SNPs shows an insignificant difference between the allele frequencies in Galloway, Hereford, Grey Ukrainian, and Black Pied herds and those in the panel. Thus, the diversity panel may be useful for identification of genetic markers associated with economically important traits in cattle, evaluation of purebred and crossbred animals, and, probably, for tentative estimation of allele frequencies in commercial populations. |
| format | Article |
| id | doaj-art-957255f207b84d229828b47242a9672a |
| institution | Kabale University |
| issn | 2500-3259 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders |
| record_format | Article |
| series | Вавиловский журнал генетики и селекции |
| spelling | doaj-art-957255f207b84d229828b47242a9672a2025-02-01T09:58:00ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592015-01-01183463468254DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDSN. S. Yudin0L. A. Vasil’eva1V. A. Belyavskaya2R. B. Aitnazarov3P. N. Smirnov4M. Heaton5W. W. Laegreid6G. V. Orlova7A. G. Romashchenko8M. I. Voevoda9Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia Institute of Internal Medicine, Novosibirsk, Russia Novosibirsk National Research State University, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaState Research Center of Virology and Biotechnology VECTOR, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaNovosibirsk State Agricultural University, Novosibirsk, RussiaMeat Animal Research Center, United States Department of Agriculture, Clay Center, USAWyoming State Veterinary Laboratory, Department of Veterinary Sciences, University of Wyoming, Laramie, USAInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Institute of Internal Medicine, Novosibirsk, Russia Novosibirsk National Research State University, Novosibirsk, RussiaA panel of 96 DNA samples that reflects the breadth of genetic diversity in popular Russian cattle breeds has been designed. The panel of cattle DNA contains 11 dairy breeds and 6 beef and beef-dairy breeds. The numbers of animals in each breed group vary from 4 to 8. The main criterion for selection of individual animals within each breed is to maximize the total number of unshared haploid genomes according to pedigree data. The resulting panel is equivalent to USDA MARC Beef Cattle Diversity Panel version 2.1 in the power of SNP identification (number of unshared haploid genomes = 186,1, minimum allele frequency required for its detection with 95 % probability – 1,6 %). Analysis of three SNPs shows an insignificant difference between the allele frequencies in Galloway, Hereford, Grey Ukrainian, and Black Pied herds and those in the panel. Thus, the diversity panel may be useful for identification of genetic markers associated with economically important traits in cattle, evaluation of purebred and crossbred animals, and, probably, for tentative estimation of allele frequencies in commercial populations.https://vavilov.elpub.ru/jour/article/view/270cattlebreedbos taurusdna panelgenetic diversityconservation geneticssnpstnf-alpha genesdf1 gene |
| spellingShingle | N. S. Yudin L. A. Vasil’eva V. A. Belyavskaya R. B. Aitnazarov P. N. Smirnov M. Heaton W. W. Laegreid G. V. Orlova A. G. Romashchenko M. I. Voevoda DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDS Вавиловский журнал генетики и селекции cattle breed bos taurus dna panel genetic diversity conservation genetics snps tnf-alpha gene sdf1 gene |
| title | DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDS |
| title_full | DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDS |
| title_fullStr | DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDS |
| title_full_unstemmed | DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDS |
| title_short | DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDS |
| title_sort | dna panel design for genomic studies in russian cattle breeds |
| topic | cattle breed bos taurus dna panel genetic diversity conservation genetics snps tnf-alpha gene sdf1 gene |
| url | https://vavilov.elpub.ru/jour/article/view/270 |
| work_keys_str_mv | AT nsyudin dnapaneldesignforgenomicstudiesinrussiancattlebreeds AT lavasileva dnapaneldesignforgenomicstudiesinrussiancattlebreeds AT vabelyavskaya dnapaneldesignforgenomicstudiesinrussiancattlebreeds AT rbaitnazarov dnapaneldesignforgenomicstudiesinrussiancattlebreeds AT pnsmirnov dnapaneldesignforgenomicstudiesinrussiancattlebreeds AT mheaton dnapaneldesignforgenomicstudiesinrussiancattlebreeds AT wwlaegreid dnapaneldesignforgenomicstudiesinrussiancattlebreeds AT gvorlova dnapaneldesignforgenomicstudiesinrussiancattlebreeds AT agromashchenko dnapaneldesignforgenomicstudiesinrussiancattlebreeds AT mivoevoda dnapaneldesignforgenomicstudiesinrussiancattlebreeds |