Bilateral One-Stage Revision of Infected Total Hip Arthroplasties: Report of Two Cases and Management of Antibiotic Therapy

Recommendations for the management of chronic and bilateral total hip arthroplasty (THA) infection are lacking. However, this type of infection involves medical problems concerning the management of the antibiotic therapy. We report two cases of such infections operated as one-stage revision. For ea...

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Main Authors: Thomas Pommepuy, Adrien Lons, Kevin Benad, Eric Beltrand, Eric Senneville, Henri Migaud
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2016/3621749
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author Thomas Pommepuy
Adrien Lons
Kevin Benad
Eric Beltrand
Eric Senneville
Henri Migaud
author_facet Thomas Pommepuy
Adrien Lons
Kevin Benad
Eric Beltrand
Eric Senneville
Henri Migaud
author_sort Thomas Pommepuy
collection DOAJ
description Recommendations for the management of chronic and bilateral total hip arthroplasty (THA) infection are lacking. However, this type of infection involves medical problems concerning the management of the antibiotic therapy. We report two cases of such infections operated as one-stage revision. For each case, both hips were infected with the same bacteria (Staphylococcus caprae for one patient and methicillin-sensitive Staphylococcus aureus for the other). The probabilistic antibiotic treatment started during the first side (after harvesting intraoperative samples) did not prevent the culture of the bacteriologic harvested during the intervention of the second side. Cultures were positive for the same bacteria for both sides in the two cases presented herein. After results of intraoperative cultures, patients received culture-guided antibiotic therapy for three months and were considered cured at the end of a two-year follow-up. Our results suggest one-stage bilateral change of infected THA is a viable option and that early intraoperative antibiotic, started during the first-side exchange, does not jeopardize microbiological documentation of the second side. This work brings indirect arguments, in favor of the use of prophylactic antibiotics during revision of infected THA.
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spelling doaj-art-956dfee32f544575bd4049bd70f5e2992025-02-03T01:29:09ZengWileyCase Reports in Orthopedics2090-67492090-67572016-01-01201610.1155/2016/36217493621749Bilateral One-Stage Revision of Infected Total Hip Arthroplasties: Report of Two Cases and Management of Antibiotic TherapyThomas Pommepuy0Adrien Lons1Kevin Benad2Eric Beltrand3Eric Senneville4Henri Migaud5University of Lille, 59000 Lille, FranceUniversity of Lille, 59000 Lille, FranceUniversity of Lille, 59000 Lille, FranceNorthwest Reference Center for Osteoarticular Infections (CRIOAC-G4 Lille-Tourcoing), Lille University Hospital, rue Emile-Laine, 59037 Lille, FranceUniversity of Lille, 59000 Lille, FranceUniversity of Lille, 59000 Lille, FranceRecommendations for the management of chronic and bilateral total hip arthroplasty (THA) infection are lacking. However, this type of infection involves medical problems concerning the management of the antibiotic therapy. We report two cases of such infections operated as one-stage revision. For each case, both hips were infected with the same bacteria (Staphylococcus caprae for one patient and methicillin-sensitive Staphylococcus aureus for the other). The probabilistic antibiotic treatment started during the first side (after harvesting intraoperative samples) did not prevent the culture of the bacteriologic harvested during the intervention of the second side. Cultures were positive for the same bacteria for both sides in the two cases presented herein. After results of intraoperative cultures, patients received culture-guided antibiotic therapy for three months and were considered cured at the end of a two-year follow-up. Our results suggest one-stage bilateral change of infected THA is a viable option and that early intraoperative antibiotic, started during the first-side exchange, does not jeopardize microbiological documentation of the second side. This work brings indirect arguments, in favor of the use of prophylactic antibiotics during revision of infected THA.http://dx.doi.org/10.1155/2016/3621749
spellingShingle Thomas Pommepuy
Adrien Lons
Kevin Benad
Eric Beltrand
Eric Senneville
Henri Migaud
Bilateral One-Stage Revision of Infected Total Hip Arthroplasties: Report of Two Cases and Management of Antibiotic Therapy
Case Reports in Orthopedics
title Bilateral One-Stage Revision of Infected Total Hip Arthroplasties: Report of Two Cases and Management of Antibiotic Therapy
title_full Bilateral One-Stage Revision of Infected Total Hip Arthroplasties: Report of Two Cases and Management of Antibiotic Therapy
title_fullStr Bilateral One-Stage Revision of Infected Total Hip Arthroplasties: Report of Two Cases and Management of Antibiotic Therapy
title_full_unstemmed Bilateral One-Stage Revision of Infected Total Hip Arthroplasties: Report of Two Cases and Management of Antibiotic Therapy
title_short Bilateral One-Stage Revision of Infected Total Hip Arthroplasties: Report of Two Cases and Management of Antibiotic Therapy
title_sort bilateral one stage revision of infected total hip arthroplasties report of two cases and management of antibiotic therapy
url http://dx.doi.org/10.1155/2016/3621749
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