Clear Cell Carcinoma of the Endometrium Causing Paraneoplastic Retinopathy: Case Report and Review of the Literature
We reviewed the literature for cases in which gynecologic malignancies caused paraneoplastic retinopathy and ultimately led to blindness. Twenty-eight cases were derived from the literature, and one unique case is described from our institution. Of these 28 cases, 14 patients were diagnosed with end...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2011/631929 |
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| author | Paulina Cybulska Eduardo V. Navajas Filiberto Altomare Marcus Q. Bernardini |
| author_facet | Paulina Cybulska Eduardo V. Navajas Filiberto Altomare Marcus Q. Bernardini |
| author_sort | Paulina Cybulska |
| collection | DOAJ |
| description | We reviewed the literature for cases in which gynecologic malignancies caused paraneoplastic retinopathy and ultimately led to blindness. Twenty-eight cases were derived from the literature, and one unique case is described from our institution. Of these 28 cases, 14 patients were diagnosed with endometrial cancer, 7 with ovarian cancer, 5 with cervical cancer, 1 fallopian tube cancer and 1 with concomitant endometrial and ovarian cancers. The average age of patients at the time of diagnosis was 64 years (range, 35–89 years). Typically, ocular manifestations antedate symptoms of the underlying carcinoma by 3–12 months. Information regarding the interval from visual symptoms to time of death is limited, but ranges from several months to several years. Our report is the first to document a clear cell carcinoma of the endometrium causing paraneoplastic retinopathy and is the first to review all gynecologic malignancies associated with visual paraneoplastic syndromes. |
| format | Article |
| id | doaj-art-9565c93c05e849b2b7b773d504c877db |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-9565c93c05e849b2b7b773d504c877db2025-02-03T01:01:48ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922011-01-01201110.1155/2011/631929631929Clear Cell Carcinoma of the Endometrium Causing Paraneoplastic Retinopathy: Case Report and Review of the LiteraturePaulina Cybulska0Eduardo V. Navajas1Filiberto Altomare2Marcus Q. Bernardini3Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON, M5G 0A3, CanadaDepartment of Ophthalmology and Vision Sciences, Princess Margaret Hospital, University of Toronto, Toronto, ON, M5G 2M9, CanadaDepartment of Ophthalmology and Vision Sciences, Princess Margaret Hospital, University of Toronto, Toronto, ON, M5G 2M9, CanadaDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Princess Margaret Hospital, University of Toronto, Toronto, ON, M5G 2M9, CanadaWe reviewed the literature for cases in which gynecologic malignancies caused paraneoplastic retinopathy and ultimately led to blindness. Twenty-eight cases were derived from the literature, and one unique case is described from our institution. Of these 28 cases, 14 patients were diagnosed with endometrial cancer, 7 with ovarian cancer, 5 with cervical cancer, 1 fallopian tube cancer and 1 with concomitant endometrial and ovarian cancers. The average age of patients at the time of diagnosis was 64 years (range, 35–89 years). Typically, ocular manifestations antedate symptoms of the underlying carcinoma by 3–12 months. Information regarding the interval from visual symptoms to time of death is limited, but ranges from several months to several years. Our report is the first to document a clear cell carcinoma of the endometrium causing paraneoplastic retinopathy and is the first to review all gynecologic malignancies associated with visual paraneoplastic syndromes.http://dx.doi.org/10.1155/2011/631929 |
| spellingShingle | Paulina Cybulska Eduardo V. Navajas Filiberto Altomare Marcus Q. Bernardini Clear Cell Carcinoma of the Endometrium Causing Paraneoplastic Retinopathy: Case Report and Review of the Literature Case Reports in Obstetrics and Gynecology |
| title | Clear Cell Carcinoma of the Endometrium Causing Paraneoplastic Retinopathy: Case Report and Review of the Literature |
| title_full | Clear Cell Carcinoma of the Endometrium Causing Paraneoplastic Retinopathy: Case Report and Review of the Literature |
| title_fullStr | Clear Cell Carcinoma of the Endometrium Causing Paraneoplastic Retinopathy: Case Report and Review of the Literature |
| title_full_unstemmed | Clear Cell Carcinoma of the Endometrium Causing Paraneoplastic Retinopathy: Case Report and Review of the Literature |
| title_short | Clear Cell Carcinoma of the Endometrium Causing Paraneoplastic Retinopathy: Case Report and Review of the Literature |
| title_sort | clear cell carcinoma of the endometrium causing paraneoplastic retinopathy case report and review of the literature |
| url | http://dx.doi.org/10.1155/2011/631929 |
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