Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT
Image-guided radiotherapy (IGRT), adaptive radiotherapy (ART), and online reoptimization rely on accurate mapping of the radiation beam isocenter(s) from planning to treatment space. This mapping involves rigid and/or nonrigid registration of planning (pCT) and intratreatment (tCT) CT images. The pu...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Biomedical Imaging |
| Online Access: | http://dx.doi.org/10.1155/2013/892152 |
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| author | Zijie Xu Ronald Chen Andrew Wang Andrea Kress Mark Foskey An Qin Timothy Cullip Gregg Tracton Sha Chang Joel Tepper Di Yan Edward Chaney |
| author_facet | Zijie Xu Ronald Chen Andrew Wang Andrea Kress Mark Foskey An Qin Timothy Cullip Gregg Tracton Sha Chang Joel Tepper Di Yan Edward Chaney |
| author_sort | Zijie Xu |
| collection | DOAJ |
| description | Image-guided radiotherapy (IGRT), adaptive radiotherapy (ART), and online reoptimization rely on accurate mapping of the radiation beam isocenter(s) from planning to treatment space. This mapping involves rigid and/or nonrigid registration of planning (pCT) and intratreatment (tCT) CT images. The purpose of this study was to retrospectively compare a fully automatic approach, including a non-rigid step, against a user-directed rigid method implemented in a clinical IGRT protocol for prostate cancer. Isocenters resulting from automatic and clinical mappings were compared to reference isocenters carefully determined in each tCT. Comparison was based on displacements from the reference isocenters and prostate dose-volume histograms (DVHs). Ten patients with a total of 243 tCTs were investigated. Fully automatic registration was found to be as accurate as the clinical protocol but more precise for all patients. The average of the unsigned x, y, and z offsets and the standard deviations (σ) of the signed offsets computed over all images were (avg. ± σ (mm)): 1.1 ± 1.4, 1.8 ± 2.3, 2.5 ± 3.5 for the clinical protocol and 0.6 ± 0.8, 1.1 ± 1.5 and 1.1 ± 1.4 for the automatic method. No failures or outliers from automatic mapping were observed, while 8 outliers occurred for the clinical protocol. |
| format | Article |
| id | doaj-art-9560c53d8e5d49a58cded539fed6f658 |
| institution | Kabale University |
| issn | 1687-4188 1687-4196 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomedical Imaging |
| spelling | doaj-art-9560c53d8e5d49a58cded539fed6f6582025-02-03T00:59:51ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962013-01-01201310.1155/2013/892152892152Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRTZijie Xu0Ronald Chen1Andrew Wang2Andrea Kress3Mark Foskey4An Qin5Timothy Cullip6Gregg Tracton7Sha Chang8Joel Tepper9Di Yan10Edward Chaney11Department of Radiation Oncology, CB 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USADepartment of Radiation Oncology, CB 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USADepartment of Radiation Oncology, CB 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USADepartment of Radiation Oncology, CB 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USADepartment of Radiation Oncology, CB 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USADepartment of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI, USADepartment of Radiation Oncology, CB 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USADepartment of Radiation Oncology, CB 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USADepartment of Radiation Oncology, CB 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USADepartment of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI, USADepartment of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI, USADepartment of Radiation Oncology, CB 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USAImage-guided radiotherapy (IGRT), adaptive radiotherapy (ART), and online reoptimization rely on accurate mapping of the radiation beam isocenter(s) from planning to treatment space. This mapping involves rigid and/or nonrigid registration of planning (pCT) and intratreatment (tCT) CT images. The purpose of this study was to retrospectively compare a fully automatic approach, including a non-rigid step, against a user-directed rigid method implemented in a clinical IGRT protocol for prostate cancer. Isocenters resulting from automatic and clinical mappings were compared to reference isocenters carefully determined in each tCT. Comparison was based on displacements from the reference isocenters and prostate dose-volume histograms (DVHs). Ten patients with a total of 243 tCTs were investigated. Fully automatic registration was found to be as accurate as the clinical protocol but more precise for all patients. The average of the unsigned x, y, and z offsets and the standard deviations (σ) of the signed offsets computed over all images were (avg. ± σ (mm)): 1.1 ± 1.4, 1.8 ± 2.3, 2.5 ± 3.5 for the clinical protocol and 0.6 ± 0.8, 1.1 ± 1.5 and 1.1 ± 1.4 for the automatic method. No failures or outliers from automatic mapping were observed, while 8 outliers occurred for the clinical protocol.http://dx.doi.org/10.1155/2013/892152 |
| spellingShingle | Zijie Xu Ronald Chen Andrew Wang Andrea Kress Mark Foskey An Qin Timothy Cullip Gregg Tracton Sha Chang Joel Tepper Di Yan Edward Chaney Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT International Journal of Biomedical Imaging |
| title | Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT |
| title_full | Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT |
| title_fullStr | Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT |
| title_full_unstemmed | Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT |
| title_short | Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT |
| title_sort | comparison of user directed and automatic mapping of the planned isocenter to treatment space for prostate igrt |
| url | http://dx.doi.org/10.1155/2013/892152 |
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