Effect of Sodium Salicylate on the Viscoelastic Properties and Stability of Polyacrylate-Based Hydrogels for Medical Applications
Investigation was made into the effect exerted by the presence of sodium salicylate (0–2 wt.%), in Carbomer-based hydrogel systems, on processing conditions, rheological and antimicrobial properties in tests against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacterial...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2016/5614687 |
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| _version_ | 1832561782500098048 |
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| author | Zuzana Kolarova Raskova Martina Hrabalikova Vladimir Sedlarik |
| author_facet | Zuzana Kolarova Raskova Martina Hrabalikova Vladimir Sedlarik |
| author_sort | Zuzana Kolarova Raskova |
| collection | DOAJ |
| description | Investigation was made into the effect exerted by the presence of sodium salicylate (0–2 wt.%), in Carbomer-based hydrogel systems, on processing conditions, rheological and antimicrobial properties in tests against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacterial strains, and examples of yeast (Candida albicans) and mould (Aspergillus niger). In addition, the work presents an examination of long-term stability by means of aging over one year the given hydrogels at 8°C and 25°C. The results show that 0.5 wt.% NaSal demonstrated a noticeable effect on the hydrogel neutralization process, viscosity, and antimicrobial properties against all of the tested microorganisms. The long-term stability studies revealed that hydrogels can maintain antimicrobial activity as well as viscosity to a degree that would be sufficient for practical use. |
| format | Article |
| id | doaj-art-954b7d89a927468abb018755c0f3840d |
| institution | Kabale University |
| issn | 1687-9422 1687-9430 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj-art-954b7d89a927468abb018755c0f3840d2025-02-03T01:24:17ZengWileyInternational Journal of Polymer Science1687-94221687-94302016-01-01201610.1155/2016/56146875614687Effect of Sodium Salicylate on the Viscoelastic Properties and Stability of Polyacrylate-Based Hydrogels for Medical ApplicationsZuzana Kolarova Raskova0Martina Hrabalikova1Vladimir Sedlarik2Centre of Polymer Systems, University Institute, Tomas Bata University in Zlin, Trida T. Bati 5678, 76001 Zlín, Czech RepublicCentre of Polymer Systems, University Institute, Tomas Bata University in Zlin, Trida T. Bati 5678, 76001 Zlín, Czech RepublicCentre of Polymer Systems, University Institute, Tomas Bata University in Zlin, Trida T. Bati 5678, 76001 Zlín, Czech RepublicInvestigation was made into the effect exerted by the presence of sodium salicylate (0–2 wt.%), in Carbomer-based hydrogel systems, on processing conditions, rheological and antimicrobial properties in tests against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacterial strains, and examples of yeast (Candida albicans) and mould (Aspergillus niger). In addition, the work presents an examination of long-term stability by means of aging over one year the given hydrogels at 8°C and 25°C. The results show that 0.5 wt.% NaSal demonstrated a noticeable effect on the hydrogel neutralization process, viscosity, and antimicrobial properties against all of the tested microorganisms. The long-term stability studies revealed that hydrogels can maintain antimicrobial activity as well as viscosity to a degree that would be sufficient for practical use.http://dx.doi.org/10.1155/2016/5614687 |
| spellingShingle | Zuzana Kolarova Raskova Martina Hrabalikova Vladimir Sedlarik Effect of Sodium Salicylate on the Viscoelastic Properties and Stability of Polyacrylate-Based Hydrogels for Medical Applications International Journal of Polymer Science |
| title | Effect of Sodium Salicylate on the Viscoelastic Properties and Stability of Polyacrylate-Based Hydrogels for Medical Applications |
| title_full | Effect of Sodium Salicylate on the Viscoelastic Properties and Stability of Polyacrylate-Based Hydrogels for Medical Applications |
| title_fullStr | Effect of Sodium Salicylate on the Viscoelastic Properties and Stability of Polyacrylate-Based Hydrogels for Medical Applications |
| title_full_unstemmed | Effect of Sodium Salicylate on the Viscoelastic Properties and Stability of Polyacrylate-Based Hydrogels for Medical Applications |
| title_short | Effect of Sodium Salicylate on the Viscoelastic Properties and Stability of Polyacrylate-Based Hydrogels for Medical Applications |
| title_sort | effect of sodium salicylate on the viscoelastic properties and stability of polyacrylate based hydrogels for medical applications |
| url | http://dx.doi.org/10.1155/2016/5614687 |
| work_keys_str_mv | AT zuzanakolarovaraskova effectofsodiumsalicylateontheviscoelasticpropertiesandstabilityofpolyacrylatebasedhydrogelsformedicalapplications AT martinahrabalikova effectofsodiumsalicylateontheviscoelasticpropertiesandstabilityofpolyacrylatebasedhydrogelsformedicalapplications AT vladimirsedlarik effectofsodiumsalicylateontheviscoelasticpropertiesandstabilityofpolyacrylatebasedhydrogelsformedicalapplications |