Intra-Attack Vestibuloocular Reflex Changes in Ménière’s Disease
Ménière’s attack has been shown to temporarily alter the vestibuloocular reflex (VOR). A patient with unilateral Ménière’s disease was serially evaluated with the video Head Impulse Test during single, untreated episodes of acute vertigo. Spontaneous nystagmus activity was concurrently recorded in o...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2016/2427983 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832545590574055424 |
|---|---|
| author | Dario A. Yacovino John B. Finlay |
| author_facet | Dario A. Yacovino John B. Finlay |
| author_sort | Dario A. Yacovino |
| collection | DOAJ |
| description | Ménière’s attack has been shown to temporarily alter the vestibuloocular reflex (VOR). A patient with unilateral Ménière’s disease was serially evaluated with the video Head Impulse Test during single, untreated episodes of acute vertigo. Spontaneous nystagmus activity was concurrently recorded in order to establish the three typical phases of Ménière’s attack (irritative, paralytic, and recovery) and correlate them with VOR performance. The onset of attack was associated with a quick change in VOR gain on the side of the affected ear. While a rapidly progressive reduction of the VOR was evident at the paralytic nystagmus phase, in the recovery phase the VOR gain returned to normal and the direction of the previous nystagmus reversed. The membrane rupture potassium intoxication theory provides a good foundation with which to explain these dynamic VOR changes and the observed triphasic direction behavior of the spontaneous nystagmus. We additionally postulated that endolymphatic fluid displacement could have a synergic effect during the earliest phase of attack. |
| format | Article |
| id | doaj-art-95348b6acf554feea866e3009e297afd |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-95348b6acf554feea866e3009e297afd2025-02-03T07:25:24ZengWileyCase Reports in Otolaryngology2090-67652090-67732016-01-01201610.1155/2016/24279832427983Intra-Attack Vestibuloocular Reflex Changes in Ménière’s DiseaseDario A. Yacovino0John B. Finlay1Department of Neurology, Cesar Milstein Hospital, Buenos Aires, ArgentinaDepartment of Neurology, Cesar Milstein Hospital, Buenos Aires, ArgentinaMénière’s attack has been shown to temporarily alter the vestibuloocular reflex (VOR). A patient with unilateral Ménière’s disease was serially evaluated with the video Head Impulse Test during single, untreated episodes of acute vertigo. Spontaneous nystagmus activity was concurrently recorded in order to establish the three typical phases of Ménière’s attack (irritative, paralytic, and recovery) and correlate them with VOR performance. The onset of attack was associated with a quick change in VOR gain on the side of the affected ear. While a rapidly progressive reduction of the VOR was evident at the paralytic nystagmus phase, in the recovery phase the VOR gain returned to normal and the direction of the previous nystagmus reversed. The membrane rupture potassium intoxication theory provides a good foundation with which to explain these dynamic VOR changes and the observed triphasic direction behavior of the spontaneous nystagmus. We additionally postulated that endolymphatic fluid displacement could have a synergic effect during the earliest phase of attack.http://dx.doi.org/10.1155/2016/2427983 |
| spellingShingle | Dario A. Yacovino John B. Finlay Intra-Attack Vestibuloocular Reflex Changes in Ménière’s Disease Case Reports in Otolaryngology |
| title | Intra-Attack Vestibuloocular Reflex Changes in Ménière’s Disease |
| title_full | Intra-Attack Vestibuloocular Reflex Changes in Ménière’s Disease |
| title_fullStr | Intra-Attack Vestibuloocular Reflex Changes in Ménière’s Disease |
| title_full_unstemmed | Intra-Attack Vestibuloocular Reflex Changes in Ménière’s Disease |
| title_short | Intra-Attack Vestibuloocular Reflex Changes in Ménière’s Disease |
| title_sort | intra attack vestibuloocular reflex changes in meniere s disease |
| url | http://dx.doi.org/10.1155/2016/2427983 |
| work_keys_str_mv | AT darioayacovino intraattackvestibuloocularreflexchangesinmenieresdisease AT johnbfinlay intraattackvestibuloocularreflexchangesinmenieresdisease |