Local treatment of HVJ-E with T cell costimulatory molecule stimulation elicits systemic anti-tumor effects

Local treatment of HVJ-E with T cell costimulatory molecule stimulation elicits systemic anti-tumor effects

The tumor-infiltrating lymphocyte (TIL) is a crucial factor in controlling tumor growth. A therapeutic method activating TIL is desired for treating patients with metastatic tumors. Here, we show that treating a local tumor with a combination therapy of UV-irradiated hemagglutinating virus of Japan...

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Bibliographic Details
Main Authors: Airi Ishibashi, Yue Li, Yuuta Hisatomi, Noriko Ohta, Yuko Uegaki, Atsushi Tanemura, Riuko Ohashi, Koji Kitamura, Kotaro Saga, Yasuhide Yoshimura, Satoko Inubushi, Kyoso Ishida, Sadahiro Iwabuchi, Shinichi Hashimoto, Eiji Kiyohara, Hideo Yagita, Yasufumi Kaneda, Keisuke Nimura
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Molecular Therapy: Oncology
Subjects:
Sendai virus
HVJ
HVJ-E
OX40
Nkg2d
Nkg2d ligand
Online Access:http://www.sciencedirect.com/science/article/pii/S2950329924001358
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