Autoimmune Hemolytic Anemia and Hodgkin’s Disease: An Unusual Pediatric Association

Autoimmune hemolytic anemia (AIHA) is a recognized complication of lymphoproliferative disorders. AIHA associated with Hodgkin’s disease (HD) is uncommon especially in the pediatric population. The diagnosis of AIHA is usually associated with HD at the time of initial presentation or during the cour...

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Main Authors: Maria Miguel Gomes, Tereza Oliva, Armando Pinto
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2016/4598587
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author Maria Miguel Gomes
Tereza Oliva
Armando Pinto
author_facet Maria Miguel Gomes
Tereza Oliva
Armando Pinto
author_sort Maria Miguel Gomes
collection DOAJ
description Autoimmune hemolytic anemia (AIHA) is a recognized complication of lymphoproliferative disorders. AIHA associated with Hodgkin’s disease (HD) is uncommon especially in the pediatric population. The diagnosis of AIHA is usually associated with HD at the time of initial presentation or during the course of disease, but it could precede it by years to months. In adults the association of AIHA and HD is more frequent in advanced stages and in the nodular sclerosis and mixed cellularity type HD. Warm immune hemolytic anemia is mainly controlled with steroids and chemotherapy. We report a case of a pediatric patient with direct antiglobulin positive test at the diagnosis of a late relapse of stage III B mixed cellularity type HD.
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spelling doaj-art-951d5760cf1645f684a0fa54350ea0ea2025-02-03T01:27:26ZengWileyCase Reports in Pediatrics2090-68032090-68112016-01-01201610.1155/2016/45985874598587Autoimmune Hemolytic Anemia and Hodgkin’s Disease: An Unusual Pediatric AssociationMaria Miguel Gomes0Tereza Oliva1Armando Pinto2Department of Pediatrics, Hospital de Braga, Sete Fontes, São Victor, 4710-243 Braga, PortugalDepartment of Pediatrics, Portuguese Oncology Institute of Porto Francisco Gentil, 4200-072 Porto, PortugalDepartment of Pediatrics, Portuguese Oncology Institute of Porto Francisco Gentil, 4200-072 Porto, PortugalAutoimmune hemolytic anemia (AIHA) is a recognized complication of lymphoproliferative disorders. AIHA associated with Hodgkin’s disease (HD) is uncommon especially in the pediatric population. The diagnosis of AIHA is usually associated with HD at the time of initial presentation or during the course of disease, but it could precede it by years to months. In adults the association of AIHA and HD is more frequent in advanced stages and in the nodular sclerosis and mixed cellularity type HD. Warm immune hemolytic anemia is mainly controlled with steroids and chemotherapy. We report a case of a pediatric patient with direct antiglobulin positive test at the diagnosis of a late relapse of stage III B mixed cellularity type HD.http://dx.doi.org/10.1155/2016/4598587
spellingShingle Maria Miguel Gomes
Tereza Oliva
Armando Pinto
Autoimmune Hemolytic Anemia and Hodgkin’s Disease: An Unusual Pediatric Association
Case Reports in Pediatrics
title Autoimmune Hemolytic Anemia and Hodgkin’s Disease: An Unusual Pediatric Association
title_full Autoimmune Hemolytic Anemia and Hodgkin’s Disease: An Unusual Pediatric Association
title_fullStr Autoimmune Hemolytic Anemia and Hodgkin’s Disease: An Unusual Pediatric Association
title_full_unstemmed Autoimmune Hemolytic Anemia and Hodgkin’s Disease: An Unusual Pediatric Association
title_short Autoimmune Hemolytic Anemia and Hodgkin’s Disease: An Unusual Pediatric Association
title_sort autoimmune hemolytic anemia and hodgkin s disease an unusual pediatric association
url http://dx.doi.org/10.1155/2016/4598587
work_keys_str_mv AT mariamiguelgomes autoimmunehemolyticanemiaandhodgkinsdiseaseanunusualpediatricassociation
AT terezaoliva autoimmunehemolyticanemiaandhodgkinsdiseaseanunusualpediatricassociation
AT armandopinto autoimmunehemolyticanemiaandhodgkinsdiseaseanunusualpediatricassociation