Impact of Coronary Artery Disease and Diabetes Mellitus on the Long-Term Follow-Up in Patients after Retrograde Recanalization of the Femoropopliteal Arterial Region
The most relevant comorbidities in patients with peripheral artery disease (PAD) are coronary artery disease (CAD) and diabetes mellitus (DM). However, data of long-term follow-up of patients with chronic total occlusion (CTO) are scarce. The aim of the study was to assess the impact of CAD and DM o...
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| Format: | Article |
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Wiley
2019-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2019/6036359 |
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| author | Joanna Wojtasik-Bakalarz Zoltan Ruzsa Tomasz Rakowski Andreas Nyerges Krzysztof Bartuś Agata Stanek Dariusz Dudek Andrzej Surdacki Paweł Kleczyński Stanisław Bartuś |
| author_facet | Joanna Wojtasik-Bakalarz Zoltan Ruzsa Tomasz Rakowski Andreas Nyerges Krzysztof Bartuś Agata Stanek Dariusz Dudek Andrzej Surdacki Paweł Kleczyński Stanisław Bartuś |
| author_sort | Joanna Wojtasik-Bakalarz |
| collection | DOAJ |
| description | The most relevant comorbidities in patients with peripheral artery disease (PAD) are coronary artery disease (CAD) and diabetes mellitus (DM). However, data of long-term follow-up of patients with chronic total occlusion (CTO) are scarce. The aim of the study was to assess the impact of CAD and DM on long-term follow-up patients after superficial femoral artery (SFA) CTO retrograde recanalization. In this study, eighty-six patients with PAD with diagnosed CTO in the femoropopliteal region and at least one unsuccessful attempt of antegrade recanalization were enrolled in 2 clinical centers. Mean time of follow-up in all patients was 47.5 months (±40 months). Patients were divided into two groups depending on the presence of CAD (CAD group: n=45 vs. non-CAD group: n=41) and DM (DM group: n=50 vs. non-DM group: n=36). In long-term follow-up, major adverse peripheral events (MAPE) occurred in 66.6% of patients with CAD vs. 36.5% of patients without CAD and in 50% of patients with DM vs. 55% of non-DM subjects. There were no statistical differences in peripheral endpoints in both groups. However, there was a statistically significant difference in all-cause mortality: in the DM group, there were 6 deaths (12%) (P value = 0.038). To conclude, patients after retrograde recanalization, with coexisting CTO and DM, are at higher risk of death in long-term follow-up. |
| format | Article |
| id | doaj-art-950ce2e782394a60a948cc127604c0cf |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-950ce2e782394a60a948cc127604c0cf2025-02-03T05:59:34ZengWileyJournal of Diabetes Research2314-67452314-67532019-01-01201910.1155/2019/60363596036359Impact of Coronary Artery Disease and Diabetes Mellitus on the Long-Term Follow-Up in Patients after Retrograde Recanalization of the Femoropopliteal Arterial RegionJoanna Wojtasik-Bakalarz0Zoltan Ruzsa1Tomasz Rakowski2Andreas Nyerges3Krzysztof Bartuś4Agata Stanek5Dariusz Dudek6Andrzej Surdacki7Paweł Kleczyński8Stanisław Bartuś92nd Department of Cardiology, Jagiellonian University Collegium Medicum, Krakow, PolandSemmelweis University, Heart and Vascular Center, Cardiology Department, Hungary2nd Department of Cardiology, Jagiellonian University Collegium Medicum, Krakow, PolandSemmelweis University, Heart and Vascular Center, Cardiology Department, Hungary2nd Department of Cardiology, Jagiellonian University Collegium Medicum, Krakow, PolandDepartment of Internal Medicine, Angiology and Physical Medicine, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Bytom, Poland2nd Department of Cardiology, Jagiellonian University Collegium Medicum, Krakow, Poland2nd Department of Cardiology, Jagiellonian University Collegium Medicum, Krakow, Poland2nd Department of Cardiology, Jagiellonian University Collegium Medicum, Krakow, Poland2nd Department of Cardiology, Jagiellonian University Collegium Medicum, Krakow, PolandThe most relevant comorbidities in patients with peripheral artery disease (PAD) are coronary artery disease (CAD) and diabetes mellitus (DM). However, data of long-term follow-up of patients with chronic total occlusion (CTO) are scarce. The aim of the study was to assess the impact of CAD and DM on long-term follow-up patients after superficial femoral artery (SFA) CTO retrograde recanalization. In this study, eighty-six patients with PAD with diagnosed CTO in the femoropopliteal region and at least one unsuccessful attempt of antegrade recanalization were enrolled in 2 clinical centers. Mean time of follow-up in all patients was 47.5 months (±40 months). Patients were divided into two groups depending on the presence of CAD (CAD group: n=45 vs. non-CAD group: n=41) and DM (DM group: n=50 vs. non-DM group: n=36). In long-term follow-up, major adverse peripheral events (MAPE) occurred in 66.6% of patients with CAD vs. 36.5% of patients without CAD and in 50% of patients with DM vs. 55% of non-DM subjects. There were no statistical differences in peripheral endpoints in both groups. However, there was a statistically significant difference in all-cause mortality: in the DM group, there were 6 deaths (12%) (P value = 0.038). To conclude, patients after retrograde recanalization, with coexisting CTO and DM, are at higher risk of death in long-term follow-up.http://dx.doi.org/10.1155/2019/6036359 |
| spellingShingle | Joanna Wojtasik-Bakalarz Zoltan Ruzsa Tomasz Rakowski Andreas Nyerges Krzysztof Bartuś Agata Stanek Dariusz Dudek Andrzej Surdacki Paweł Kleczyński Stanisław Bartuś Impact of Coronary Artery Disease and Diabetes Mellitus on the Long-Term Follow-Up in Patients after Retrograde Recanalization of the Femoropopliteal Arterial Region Journal of Diabetes Research |
| title | Impact of Coronary Artery Disease and Diabetes Mellitus on the Long-Term Follow-Up in Patients after Retrograde Recanalization of the Femoropopliteal Arterial Region |
| title_full | Impact of Coronary Artery Disease and Diabetes Mellitus on the Long-Term Follow-Up in Patients after Retrograde Recanalization of the Femoropopliteal Arterial Region |
| title_fullStr | Impact of Coronary Artery Disease and Diabetes Mellitus on the Long-Term Follow-Up in Patients after Retrograde Recanalization of the Femoropopliteal Arterial Region |
| title_full_unstemmed | Impact of Coronary Artery Disease and Diabetes Mellitus on the Long-Term Follow-Up in Patients after Retrograde Recanalization of the Femoropopliteal Arterial Region |
| title_short | Impact of Coronary Artery Disease and Diabetes Mellitus on the Long-Term Follow-Up in Patients after Retrograde Recanalization of the Femoropopliteal Arterial Region |
| title_sort | impact of coronary artery disease and diabetes mellitus on the long term follow up in patients after retrograde recanalization of the femoropopliteal arterial region |
| url | http://dx.doi.org/10.1155/2019/6036359 |
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