EPSTEIN-BARR VIRUS INFECTION MASQUERADING AS ACUTE LEUKEMIA: A REPORT OF TWO CASES AND REVIEW OF LITERATURE
Epstein-Barr virus (EBV) is the first herpes virus to be completely sequenced. It is implicated in diseases from the benign infectious mononucleosis to malignant nasopharyngeal carcinoma, Burkitt’s lymphoma and primary CNS lymphoma in AIDS patients. It has also been found to be associated with some...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2014-08-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | https://mjhid.org/index.php/mjhid/article/view/1845 |
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| _version_ | 1850215663900033024 |
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| author | puneet chhabra Dr arjun dutt Law Dr upender sharma Dr man updesh singh sachdeva dr vikas suri prof savita kumari prof subhash varma dr pankaj malhotra |
| author_facet | puneet chhabra Dr arjun dutt Law Dr upender sharma Dr man updesh singh sachdeva dr vikas suri prof savita kumari prof subhash varma dr pankaj malhotra |
| author_sort | puneet chhabra |
| collection | DOAJ |
| description | Epstein-Barr virus (EBV) is the first herpes virus to be completely sequenced. It is implicated in diseases from the benign infectious mononucleosis to malignant nasopharyngeal carcinoma, Burkitt’s lymphoma and primary CNS lymphoma in AIDS patients. It has also been found to be associated with some miscellaneous diseases like chronic fatigue syndrome, multiple sclerosis etc. however causality still remains an issue of debate. As the virus mainly targets the lymphomononuclear cells and the reticuloendothelial system of the body, it’s various manifestations are often mistaken as leukemic malignancies. We report two such cases of young adults who had been diagnosed as having acute leukemia on the basis of atypical cells in the peripheral blood. One patient later turned out to be a classical infectious mononucleosis and second patient had EBV associated hemophagocytic lymphohistiocytosis syndrome. |
| format | Article |
| id | doaj-art-94e23cbd08d04c83a6cfc9d156635ede |
| institution | OA Journals |
| issn | 2035-3006 |
| language | English |
| publishDate | 2014-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-94e23cbd08d04c83a6cfc9d156635ede2025-08-20T02:08:32ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011EPSTEIN-BARR VIRUS INFECTION MASQUERADING AS ACUTE LEUKEMIA: A REPORT OF TWO CASES AND REVIEW OF LITERATUREpuneet chhabraDr arjun dutt LawDr upender sharmaDr man updesh singh sachdevadr vikas suriprof savita kumariprof subhash varmadr pankaj malhotraEpstein-Barr virus (EBV) is the first herpes virus to be completely sequenced. It is implicated in diseases from the benign infectious mononucleosis to malignant nasopharyngeal carcinoma, Burkitt’s lymphoma and primary CNS lymphoma in AIDS patients. It has also been found to be associated with some miscellaneous diseases like chronic fatigue syndrome, multiple sclerosis etc. however causality still remains an issue of debate. As the virus mainly targets the lymphomononuclear cells and the reticuloendothelial system of the body, it’s various manifestations are often mistaken as leukemic malignancies. We report two such cases of young adults who had been diagnosed as having acute leukemia on the basis of atypical cells in the peripheral blood. One patient later turned out to be a classical infectious mononucleosis and second patient had EBV associated hemophagocytic lymphohistiocytosis syndrome.https://mjhid.org/index.php/mjhid/article/view/1845Epstein barr virusAcute leukemiaInfectious mononucleosisHemophagocytic lymphohistiocytosis |
| spellingShingle | puneet chhabra Dr arjun dutt Law Dr upender sharma Dr man updesh singh sachdeva dr vikas suri prof savita kumari prof subhash varma dr pankaj malhotra EPSTEIN-BARR VIRUS INFECTION MASQUERADING AS ACUTE LEUKEMIA: A REPORT OF TWO CASES AND REVIEW OF LITERATURE Mediterranean Journal of Hematology and Infectious Diseases Epstein barr virus Acute leukemia Infectious mononucleosis Hemophagocytic lymphohistiocytosis |
| title | EPSTEIN-BARR VIRUS INFECTION MASQUERADING AS ACUTE LEUKEMIA: A REPORT OF TWO CASES AND REVIEW OF LITERATURE |
| title_full | EPSTEIN-BARR VIRUS INFECTION MASQUERADING AS ACUTE LEUKEMIA: A REPORT OF TWO CASES AND REVIEW OF LITERATURE |
| title_fullStr | EPSTEIN-BARR VIRUS INFECTION MASQUERADING AS ACUTE LEUKEMIA: A REPORT OF TWO CASES AND REVIEW OF LITERATURE |
| title_full_unstemmed | EPSTEIN-BARR VIRUS INFECTION MASQUERADING AS ACUTE LEUKEMIA: A REPORT OF TWO CASES AND REVIEW OF LITERATURE |
| title_short | EPSTEIN-BARR VIRUS INFECTION MASQUERADING AS ACUTE LEUKEMIA: A REPORT OF TWO CASES AND REVIEW OF LITERATURE |
| title_sort | epstein barr virus infection masquerading as acute leukemia a report of two cases and review of literature |
| topic | Epstein barr virus Acute leukemia Infectious mononucleosis Hemophagocytic lymphohistiocytosis |
| url | https://mjhid.org/index.php/mjhid/article/view/1845 |
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