The Global Dynamics of an Age-Structured Hand-Foot-Mouth Disease Model with Saturation Incidence and Time Delay

The global dynamic behavior of an age-structured hand-foot-mouth disease (HFMD) model with saturation incidence and time delay is investigated in the work. The time delay occurs during the transition from latent to infectious individuals. Firstly, the model is expressed as an abstract Cauchy problem...

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Main Authors: Dongxue Yan, Mengqi Zhang, Jiashan Tang
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Discrete Dynamics in Nature and Society
Online Access:http://dx.doi.org/10.1155/2023/7090661
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author Dongxue Yan
Mengqi Zhang
Jiashan Tang
author_facet Dongxue Yan
Mengqi Zhang
Jiashan Tang
author_sort Dongxue Yan
collection DOAJ
description The global dynamic behavior of an age-structured hand-foot-mouth disease (HFMD) model with saturation incidence and time delay is investigated in the work. The time delay occurs during the transition from latent to infectious individuals. Firstly, the model is expressed as an abstract Cauchy problem. The presence of equilibria is then pointed; meanwhile, we define the model’s basic reproduction number R0. The conclusions show that a threshold of R0=1 can be used to evaluate whether the disease is on the verge of extinction or is still present. When R0<1, the disease-free equilibrium is globally stable. While R0>1, there exists an endemic equilibrium, and the global stability of the endemic equilibrium is also demonstrated. Finally, some numerical examples are given to demonstrate the obtained conclusions.
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series Discrete Dynamics in Nature and Society
spelling doaj-art-94df828133754859ae2f20a0dd4c552a2025-02-03T06:08:39ZengWileyDiscrete Dynamics in Nature and Society1607-887X2023-01-01202310.1155/2023/7090661The Global Dynamics of an Age-Structured Hand-Foot-Mouth Disease Model with Saturation Incidence and Time DelayDongxue Yan0Mengqi Zhang1Jiashan Tang2College of ScienceCollege of ScienceCollege of ScienceThe global dynamic behavior of an age-structured hand-foot-mouth disease (HFMD) model with saturation incidence and time delay is investigated in the work. The time delay occurs during the transition from latent to infectious individuals. Firstly, the model is expressed as an abstract Cauchy problem. The presence of equilibria is then pointed; meanwhile, we define the model’s basic reproduction number R0. The conclusions show that a threshold of R0=1 can be used to evaluate whether the disease is on the verge of extinction or is still present. When R0<1, the disease-free equilibrium is globally stable. While R0>1, there exists an endemic equilibrium, and the global stability of the endemic equilibrium is also demonstrated. Finally, some numerical examples are given to demonstrate the obtained conclusions.http://dx.doi.org/10.1155/2023/7090661
spellingShingle Dongxue Yan
Mengqi Zhang
Jiashan Tang
The Global Dynamics of an Age-Structured Hand-Foot-Mouth Disease Model with Saturation Incidence and Time Delay
Discrete Dynamics in Nature and Society
title The Global Dynamics of an Age-Structured Hand-Foot-Mouth Disease Model with Saturation Incidence and Time Delay
title_full The Global Dynamics of an Age-Structured Hand-Foot-Mouth Disease Model with Saturation Incidence and Time Delay
title_fullStr The Global Dynamics of an Age-Structured Hand-Foot-Mouth Disease Model with Saturation Incidence and Time Delay
title_full_unstemmed The Global Dynamics of an Age-Structured Hand-Foot-Mouth Disease Model with Saturation Incidence and Time Delay
title_short The Global Dynamics of an Age-Structured Hand-Foot-Mouth Disease Model with Saturation Incidence and Time Delay
title_sort global dynamics of an age structured hand foot mouth disease model with saturation incidence and time delay
url http://dx.doi.org/10.1155/2023/7090661
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