A Case of Rosai-Dorfman Disease Successfully Treated by Corticotherapy
Rosai-Dorfman disease (RDD) is a benign histiocytic proliferation that results in nodal and extranodal involvements. It is a rare disease, with fewer than 1,000 cases reported in the literature, which explains its lack of knowledge by physicians and the lack of codified therapeutic strategies. We re...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2024/9965038 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832553138558599168 |
|---|---|
| author | Alioune Badara Diallo Moustapha Ndiaye Moussa Seck Mohamed Keita Elimane Seydi Bousso Sokhna Aissatou Touré Blaise Félix Faye Saliou Diop |
| author_facet | Alioune Badara Diallo Moustapha Ndiaye Moussa Seck Mohamed Keita Elimane Seydi Bousso Sokhna Aissatou Touré Blaise Félix Faye Saliou Diop |
| author_sort | Alioune Badara Diallo |
| collection | DOAJ |
| description | Rosai-Dorfman disease (RDD) is a benign histiocytic proliferation that results in nodal and extranodal involvements. It is a rare disease, with fewer than 1,000 cases reported in the literature, which explains its lack of knowledge by physicians and the lack of codified therapeutic strategies. We report the case of an 8-year-old girl who presented a rapidly progressive cervical lymph node mass; the diagnosis of RDD was made based on histology and immunohistochemistry. The patient was treated with oral corticosteroids at a dose of 1 mg/kg/d with a favorable outcome and no recurrence after one year of follow-up. This observation illustrates the clinical presentation and diagnosis of this rare clinicopathological entity. The prognosis and treatment options are also discussed. |
| format | Article |
| id | doaj-art-94daea0549614a1b87576925a23a1ed4 |
| institution | Kabale University |
| issn | 2090-6579 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-94daea0549614a1b87576925a23a1ed42025-02-03T05:55:20ZengWileyCase Reports in Hematology2090-65792024-01-01202410.1155/2024/9965038A Case of Rosai-Dorfman Disease Successfully Treated by CorticotherapyAlioune Badara Diallo0Moustapha Ndiaye1Moussa Seck2Mohamed Keita3Elimane Seydi Bousso4Sokhna Aissatou Touré5Blaise Félix Faye6Saliou Diop7Hematology DepartmentENT DepartmentHematology DepartmentHematology DepartmentHematology DepartmentHematology DepartmentHematology DepartmentHematology DepartmentRosai-Dorfman disease (RDD) is a benign histiocytic proliferation that results in nodal and extranodal involvements. It is a rare disease, with fewer than 1,000 cases reported in the literature, which explains its lack of knowledge by physicians and the lack of codified therapeutic strategies. We report the case of an 8-year-old girl who presented a rapidly progressive cervical lymph node mass; the diagnosis of RDD was made based on histology and immunohistochemistry. The patient was treated with oral corticosteroids at a dose of 1 mg/kg/d with a favorable outcome and no recurrence after one year of follow-up. This observation illustrates the clinical presentation and diagnosis of this rare clinicopathological entity. The prognosis and treatment options are also discussed.http://dx.doi.org/10.1155/2024/9965038 |
| spellingShingle | Alioune Badara Diallo Moustapha Ndiaye Moussa Seck Mohamed Keita Elimane Seydi Bousso Sokhna Aissatou Touré Blaise Félix Faye Saliou Diop A Case of Rosai-Dorfman Disease Successfully Treated by Corticotherapy Case Reports in Hematology |
| title | A Case of Rosai-Dorfman Disease Successfully Treated by Corticotherapy |
| title_full | A Case of Rosai-Dorfman Disease Successfully Treated by Corticotherapy |
| title_fullStr | A Case of Rosai-Dorfman Disease Successfully Treated by Corticotherapy |
| title_full_unstemmed | A Case of Rosai-Dorfman Disease Successfully Treated by Corticotherapy |
| title_short | A Case of Rosai-Dorfman Disease Successfully Treated by Corticotherapy |
| title_sort | case of rosai dorfman disease successfully treated by corticotherapy |
| url | http://dx.doi.org/10.1155/2024/9965038 |
| work_keys_str_mv | AT aliounebadaradiallo acaseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT moustaphandiaye acaseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT moussaseck acaseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT mohamedkeita acaseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT elimaneseydibousso acaseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT sokhnaaissatoutoure acaseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT blaisefelixfaye acaseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT salioudiop acaseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT aliounebadaradiallo caseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT moustaphandiaye caseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT moussaseck caseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT mohamedkeita caseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT elimaneseydibousso caseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT sokhnaaissatoutoure caseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT blaisefelixfaye caseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy AT salioudiop caseofrosaidorfmandiseasesuccessfullytreatedbycorticotherapy |