Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases
There are limited data on referral rates and the number of patients with idiopathic pulmonary fibrosis (IPF) who are eligible for lung transplantation. The aim of the present study was to assess adherence to the consensus of the International Society for Heart and Lung Transplantation (ISHLT) for th...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Pulmonary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2024/5918042 |
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| author | Martina Sterclova Martina Doubkova Lubica Sykorova Vladimir Bartos Monika Zurkova Vladimira Lostakova Radka Mokosova Martina Plackova Ladislav Lacina Michaela Cimrova Radka Bittenglova Pavlina Lisa Pavla Musilova Daniel Dolezal Jana Psikalova Petra Ovesna Martina Koziar Vasakova |
| author_facet | Martina Sterclova Martina Doubkova Lubica Sykorova Vladimir Bartos Monika Zurkova Vladimira Lostakova Radka Mokosova Martina Plackova Ladislav Lacina Michaela Cimrova Radka Bittenglova Pavlina Lisa Pavla Musilova Daniel Dolezal Jana Psikalova Petra Ovesna Martina Koziar Vasakova |
| author_sort | Martina Sterclova |
| collection | DOAJ |
| description | There are limited data on referral rates and the number of patients with idiopathic pulmonary fibrosis (IPF) who are eligible for lung transplantation. The aim of the present study was to assess adherence to the consensus of the International Society for Heart and Lung Transplantation (ISHLT) for the referral of patients with IPF among Czech interstitial lung disease (ILD) centers. Czech patients who were diagnosed with IPF between 1999 and 2021 (n=1584) and who were less than 65 years old at the time of diagnosis were retrospectively selected from the Czech Republic of the European Multipartner Idiopathic Pulmonary Fibrosis Registry (EMPIRE). Nonsmokers and ex-smokers with a body mass index (BMI) of <32 kg/m2 (n=404) were included for further analyses. Patients with a history of cancer <5 years from the time of IPF diagnosis, patients with alcohol abuse, and patients with an accumulation of vascular comorbidities were excluded. The trajectory of individual patients was verified at the relevant ILD center. From the database of transplant patients (1999-12/2021, n=541), all patients who underwent transplantation for pulmonary fibrosis (n=186) were selected, and the diagnosis of IPF was subsequently verified from the patient’s medical records (n=67). A total of 304 IPF patients were eligible for lung transplantation. Ninety-six patients were referred to the transplant center, 50% (n=49) of whom were referred for lung transplantation. Thirty percent of potentially eligible patients not referred to the transplant center were considered to have too many comorbidities by the reporting physician, 19% of IPF patients denied lung transplantation, and 17% were not referred due to age. Among Czech patients with IPF, there may be a larger pool of potential lung transplant candidates than has been reported to the transplant center to date. |
| format | Article |
| id | doaj-art-94d509ca7d934c66ba732b7f4a1dc771 |
| institution | Kabale University |
| issn | 2090-1844 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Medicine |
| spelling | doaj-art-94d509ca7d934c66ba732b7f4a1dc7712025-02-03T07:23:25ZengWileyPulmonary Medicine2090-18442024-01-01202410.1155/2024/5918042Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung DiseasesMartina Sterclova0Martina Doubkova1Lubica Sykorova2Vladimir Bartos3Monika Zurkova4Vladimira Lostakova5Radka Mokosova6Martina Plackova7Ladislav Lacina8Michaela Cimrova9Radka Bittenglova10Pavlina Lisa11Pavla Musilova12Daniel Dolezal13Jana Psikalova14Petra Ovesna15Martina Koziar Vasakova16Department of Respiratory MedicineDepartment of Lung Diseases and TuberculosisDepartment of Lung Diseases and TuberculosisDepartment of Respiratory Medicine of the University Hospital Hradec KraloveDepartment of Lung Diseases and TuberculosisDepartment of Lung Diseases and TuberculosisDepartment of Pulmonary Diseases and Tuberculosis of the Ostrava University Hospital and MF OUDepartment of Pneumology and PhthisiologyDepartment of Respiratory MedicineDepartment of Respiratory MedicineDepartment of Pneumology and PhthisiologyDepartment of Respiratory MedicinePulmonary Department of Jihlava HospitalPulmonary DepartmentDepartment of Pneumology and AllergologyInstitute of Biostatistics and AnalysisDepartment of Respiratory Medicine of the 1st Faculty of Medicine of Charles University and Thomayer University HospitalThere are limited data on referral rates and the number of patients with idiopathic pulmonary fibrosis (IPF) who are eligible for lung transplantation. The aim of the present study was to assess adherence to the consensus of the International Society for Heart and Lung Transplantation (ISHLT) for the referral of patients with IPF among Czech interstitial lung disease (ILD) centers. Czech patients who were diagnosed with IPF between 1999 and 2021 (n=1584) and who were less than 65 years old at the time of diagnosis were retrospectively selected from the Czech Republic of the European Multipartner Idiopathic Pulmonary Fibrosis Registry (EMPIRE). Nonsmokers and ex-smokers with a body mass index (BMI) of <32 kg/m2 (n=404) were included for further analyses. Patients with a history of cancer <5 years from the time of IPF diagnosis, patients with alcohol abuse, and patients with an accumulation of vascular comorbidities were excluded. The trajectory of individual patients was verified at the relevant ILD center. From the database of transplant patients (1999-12/2021, n=541), all patients who underwent transplantation for pulmonary fibrosis (n=186) were selected, and the diagnosis of IPF was subsequently verified from the patient’s medical records (n=67). A total of 304 IPF patients were eligible for lung transplantation. Ninety-six patients were referred to the transplant center, 50% (n=49) of whom were referred for lung transplantation. Thirty percent of potentially eligible patients not referred to the transplant center were considered to have too many comorbidities by the reporting physician, 19% of IPF patients denied lung transplantation, and 17% were not referred due to age. Among Czech patients with IPF, there may be a larger pool of potential lung transplant candidates than has been reported to the transplant center to date.http://dx.doi.org/10.1155/2024/5918042 |
| spellingShingle | Martina Sterclova Martina Doubkova Lubica Sykorova Vladimir Bartos Monika Zurkova Vladimira Lostakova Radka Mokosova Martina Plackova Ladislav Lacina Michaela Cimrova Radka Bittenglova Pavlina Lisa Pavla Musilova Daniel Dolezal Jana Psikalova Petra Ovesna Martina Koziar Vasakova Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases Pulmonary Medicine |
| title | Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases |
| title_full | Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases |
| title_fullStr | Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases |
| title_full_unstemmed | Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases |
| title_short | Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases |
| title_sort | adherence to the ishlt protocol for the referral of patients with idiopathic pulmonary fibrosis to the transplantation center among of czech centers for interstitial lung diseases |
| url | http://dx.doi.org/10.1155/2024/5918042 |
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