Optimizing longifolene production in Yarrowia lipolytica via metabolic and protein engineering

Optimizing longifolene production in Yarrowia lipolytica via metabolic and protein engineering

Longifolene (C15H24) is a tricyclic sesquiterpene widely utilized in the cosmetics and fragrances due to its versatile applications. Traditional extraction methods from plants suffer from low titer and lengthy production cycles, while chemical synthesis is hampered by the compound's complex str...

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Bibliographic Details
Main Authors: Yi-Tong Yao, Xiao Zhang, Chen-Yu Wang, Yu-He Zhang, Da-Wei Li, Wei-Dong Yang, Hong-Ye Li, Li-Gong Zou
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-06-01
Series:Synthetic and Systems Biotechnology
Subjects:
Longifolene
Yarrowia lipolytica
Sesquiterpene
Molecular chaperone
Protein engineering
Isopentenol utilization pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X25000043
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http://www.sciencedirect.com/science/article/pii/S2405805X25000043

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