Gamma Knife Radiosurgery Treatment for Metastatic Melanoma of the Trigeminal Nerve and Brainstem: A Case Report and a Review of the Literature
Objective and Importance. Brainstem metastases (BSMs) are uncommon but serious complications of some cancers. They cause significant neurological deficit, and options for treatment are limited. Stereotactic radiosurgery (SRS) has been shown to be a safe and effective treatment for BSMs that prolongs...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/256962 |
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| author | Halloran E. Peterson Erik W. Larson Robert K. Fairbanks Wayne T. Lamoreaux Alexander R. Mackay Jason A. Call John J. Demakas Barton S. Cooke Christopher M. Lee |
| author_facet | Halloran E. Peterson Erik W. Larson Robert K. Fairbanks Wayne T. Lamoreaux Alexander R. Mackay Jason A. Call John J. Demakas Barton S. Cooke Christopher M. Lee |
| author_sort | Halloran E. Peterson |
| collection | DOAJ |
| description | Objective and Importance. Brainstem metastases (BSMs) are uncommon but serious complications of some cancers. They cause significant neurological deficit, and options for treatment are limited. Stereotactic radiosurgery (SRS) has been shown to be a safe and effective treatment for BSMs that prolongs survival and can preserve or in some cases improve neurological function. This case illustrates the use of repeated SRS, specifically Gamma Knife radiosurgery (GKRS) for management of a unique brainstem metastasis.
Clinical Presentation. This patient presented 5 years after the removal of a lentigo maligna melanoma from her left cheek with left sided facial numbness and paresthesias with no reported facial weakness. Initial MRI revealed a mass on the left trigeminal nerve that appeared to be a trigeminal schwannoma. Intervention. After only limited response to the first GKRS treatment, a biopsy of the tumor revealed it to be metastatic melanoma, not schwannoma. Over the next two years, the patient would receive 3 more GKRS treatments. These procedures were effective in controlling growth in the treated areas, and the patient has maintained a good quality of life. Conclusion. GKRS has proven in this case to be effective in limiting the growth of this metastatic melanoma without acute adverse effects. |
| format | Article |
| id | doaj-art-94c02229f11d40ebb2eae06f5080ce67 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-94c02229f11d40ebb2eae06f5080ce672025-02-03T00:59:50ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/256962256962Gamma Knife Radiosurgery Treatment for Metastatic Melanoma of the Trigeminal Nerve and Brainstem: A Case Report and a Review of the LiteratureHalloran E. Peterson0Erik W. Larson1Robert K. Fairbanks2Wayne T. Lamoreaux3Alexander R. Mackay4Jason A. Call5John J. Demakas6Barton S. Cooke7Christopher M. Lee8Gamma Knife of Spokane, 910 W. 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W. 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W. 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W. 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W. 5th Avenue, Suite 102, Spokane, WA 99204, USACancer Care Northwest, 910 W. 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W. 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W. 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W. 5th Avenue, Suite 102, Spokane, WA 99204, USAObjective and Importance. Brainstem metastases (BSMs) are uncommon but serious complications of some cancers. They cause significant neurological deficit, and options for treatment are limited. Stereotactic radiosurgery (SRS) has been shown to be a safe and effective treatment for BSMs that prolongs survival and can preserve or in some cases improve neurological function. This case illustrates the use of repeated SRS, specifically Gamma Knife radiosurgery (GKRS) for management of a unique brainstem metastasis. Clinical Presentation. This patient presented 5 years after the removal of a lentigo maligna melanoma from her left cheek with left sided facial numbness and paresthesias with no reported facial weakness. Initial MRI revealed a mass on the left trigeminal nerve that appeared to be a trigeminal schwannoma. Intervention. After only limited response to the first GKRS treatment, a biopsy of the tumor revealed it to be metastatic melanoma, not schwannoma. Over the next two years, the patient would receive 3 more GKRS treatments. These procedures were effective in controlling growth in the treated areas, and the patient has maintained a good quality of life. Conclusion. GKRS has proven in this case to be effective in limiting the growth of this metastatic melanoma without acute adverse effects.http://dx.doi.org/10.1155/2013/256962 |
| spellingShingle | Halloran E. Peterson Erik W. Larson Robert K. Fairbanks Wayne T. Lamoreaux Alexander R. Mackay Jason A. Call John J. Demakas Barton S. Cooke Christopher M. Lee Gamma Knife Radiosurgery Treatment for Metastatic Melanoma of the Trigeminal Nerve and Brainstem: A Case Report and a Review of the Literature Case Reports in Neurological Medicine |
| title | Gamma Knife Radiosurgery Treatment for Metastatic Melanoma of the Trigeminal Nerve and Brainstem: A Case Report and a Review of the Literature |
| title_full | Gamma Knife Radiosurgery Treatment for Metastatic Melanoma of the Trigeminal Nerve and Brainstem: A Case Report and a Review of the Literature |
| title_fullStr | Gamma Knife Radiosurgery Treatment for Metastatic Melanoma of the Trigeminal Nerve and Brainstem: A Case Report and a Review of the Literature |
| title_full_unstemmed | Gamma Knife Radiosurgery Treatment for Metastatic Melanoma of the Trigeminal Nerve and Brainstem: A Case Report and a Review of the Literature |
| title_short | Gamma Knife Radiosurgery Treatment for Metastatic Melanoma of the Trigeminal Nerve and Brainstem: A Case Report and a Review of the Literature |
| title_sort | gamma knife radiosurgery treatment for metastatic melanoma of the trigeminal nerve and brainstem a case report and a review of the literature |
| url | http://dx.doi.org/10.1155/2013/256962 |
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