Estimating and visualising multivariable Mendelian randomization analyses within a radial framework.

<h4>Background</h4>Mendelian randomization (MR) is a statistical approach using genetic variants as instrumental variables to estimate causal effects of a single exposure on an outcome. Multivariable MR (MVMR) extends this to estimate the direct effect of multiple exposures simulatiously...

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Bibliographic Details
Main Authors: Wes Spiller, Jack Bowden, Eleanor Sanderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011506
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