Formulation and Determination of Tannin and Flavonoid Levels of Anti-Acne Gel Formulation from Red Betel Leaf Extract (Piper crocatum)
Acne is a common skin condition that often occurs among teenagers and adults aged 18-23 years. Acne can be triggered by several factors, genetic, psychological, weather, stress, cosmetics, and bacterial infections. In addressing the problem of acne, a good dosage form to use is a gel preparation. Ac...
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LPPT Universitas Gadjah Mada
2024-04-01
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Series: | Journal of Food and Pharmaceutical Sciences |
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Online Access: | https://jurnal.ugm.ac.id/v3/JFPS/article/view/12644/4123 |
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author | Annisha Amelya Putri Deana Prima Minerva |
author_facet | Annisha Amelya Putri Deana Prima Minerva |
author_sort | Annisha Amelya Putri Deana |
collection | DOAJ |
description | Acne is a common skin condition that often occurs among teenagers and adults aged 18-23 years. Acne can be triggered by several factors, genetic, psychological, weather, stress, cosmetics, and bacterial infections. In addressing the problem of acne, a good dosage form to use is a gel preparation. Acne skin care by utilizing natural ingredients, one of which is red betel leaf. Red betel leaf contains phytochemical compounds, namely tannins and flavonoids, which function as antibacterial agents. The formulation of anti-acne gel is designed by varying the concentration extract, F0 (0%), F1 (10%), F2 (15%), and F3 (20%), with the aim of determining the best anti-acne gel formulation. Red betel leaf extract is tested for tannin and flavonoid levels using the UV-Vis Spectrophotometer test method. The gel preparation is examined, including organoleptic testing, pH testing, homogeneity testing, and spreading testing. The research results show that red betel leaf extract has a tannin content of 4.7056% and a flavonoid content of 0.0934%. The results of the anti-acne gel preparation study meet the requirements for organoleptic properties, pH, homogeneity, and spreading. Based on the results of various concentrations of extract, satisfactory results are obtained, with formulations F2 and F3 meeting the requirements. |
format | Article |
id | doaj-art-94a692626f7f42c58b681ed2a1813e42 |
institution | Kabale University |
issn | 2089-7200 2339-0948 |
language | English |
publishDate | 2024-04-01 |
publisher | LPPT Universitas Gadjah Mada |
record_format | Article |
series | Journal of Food and Pharmaceutical Sciences |
spelling | doaj-art-94a692626f7f42c58b681ed2a1813e422025-01-24T08:48:23ZengLPPT Universitas Gadjah MadaJournal of Food and Pharmaceutical Sciences2089-72002339-09482024-04-01121616610.22146/jfps.12644Formulation and Determination of Tannin and Flavonoid Levels of Anti-Acne Gel Formulation from Red Betel Leaf Extract (Piper crocatum)Annisha Amelya Putri Deana0Prima Minerva1Department of Cosmetology and Beauty, Faculty of Tourism and Hospitality, Padang State University, IndonesiaDepartment of Cosmetology and Beauty, Faculty of Tourism and Hospitality, Padang State University, IndonesiaAcne is a common skin condition that often occurs among teenagers and adults aged 18-23 years. Acne can be triggered by several factors, genetic, psychological, weather, stress, cosmetics, and bacterial infections. In addressing the problem of acne, a good dosage form to use is a gel preparation. Acne skin care by utilizing natural ingredients, one of which is red betel leaf. Red betel leaf contains phytochemical compounds, namely tannins and flavonoids, which function as antibacterial agents. The formulation of anti-acne gel is designed by varying the concentration extract, F0 (0%), F1 (10%), F2 (15%), and F3 (20%), with the aim of determining the best anti-acne gel formulation. Red betel leaf extract is tested for tannin and flavonoid levels using the UV-Vis Spectrophotometer test method. The gel preparation is examined, including organoleptic testing, pH testing, homogeneity testing, and spreading testing. The research results show that red betel leaf extract has a tannin content of 4.7056% and a flavonoid content of 0.0934%. The results of the anti-acne gel preparation study meet the requirements for organoleptic properties, pH, homogeneity, and spreading. Based on the results of various concentrations of extract, satisfactory results are obtained, with formulations F2 and F3 meeting the requirements.https://jurnal.ugm.ac.id/v3/JFPS/article/view/12644/4123acnegelextractpiper crocatum |
spellingShingle | Annisha Amelya Putri Deana Prima Minerva Formulation and Determination of Tannin and Flavonoid Levels of Anti-Acne Gel Formulation from Red Betel Leaf Extract (Piper crocatum) Journal of Food and Pharmaceutical Sciences acne gel extract piper crocatum |
title | Formulation and Determination of Tannin and Flavonoid Levels of Anti-Acne Gel Formulation from Red Betel Leaf Extract (Piper crocatum) |
title_full | Formulation and Determination of Tannin and Flavonoid Levels of Anti-Acne Gel Formulation from Red Betel Leaf Extract (Piper crocatum) |
title_fullStr | Formulation and Determination of Tannin and Flavonoid Levels of Anti-Acne Gel Formulation from Red Betel Leaf Extract (Piper crocatum) |
title_full_unstemmed | Formulation and Determination of Tannin and Flavonoid Levels of Anti-Acne Gel Formulation from Red Betel Leaf Extract (Piper crocatum) |
title_short | Formulation and Determination of Tannin and Flavonoid Levels of Anti-Acne Gel Formulation from Red Betel Leaf Extract (Piper crocatum) |
title_sort | formulation and determination of tannin and flavonoid levels of anti acne gel formulation from red betel leaf extract piper crocatum |
topic | acne gel extract piper crocatum |
url | https://jurnal.ugm.ac.id/v3/JFPS/article/view/12644/4123 |
work_keys_str_mv | AT annishaamelyaputrideana formulationanddeterminationoftanninandflavonoidlevelsofantiacnegelformulationfromredbetelleafextractpipercrocatum AT primaminerva formulationanddeterminationoftanninandflavonoidlevelsofantiacnegelformulationfromredbetelleafextractpipercrocatum |