In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets

The present work was to a comparative exploration of some physicochemical possessions viz., weight change, thickness, diameter, hardness, disintegration time, in-vitro drug discharge and analyse studies of various commercially available Pantoprazole sodium tablets (PST) of 40 mg. The hardness, loss...

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Main Authors: Hindustan Abdul Ahad, Chinthaginjala Haranath, Rahul Raghav Dasari, Madana Gowthami, Naga Jyothi Varam, Pandyala Sravanthi
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Kuwait Journal of Science
Subjects:
Online Access:https://journalskuwait.org/kjs/index.php/KJS/article/view/8598
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author Hindustan Abdul Ahad
Chinthaginjala Haranath
Rahul Raghav Dasari
Madana Gowthami
Naga Jyothi Varam
Pandyala Sravanthi
author_facet Hindustan Abdul Ahad
Chinthaginjala Haranath
Rahul Raghav Dasari
Madana Gowthami
Naga Jyothi Varam
Pandyala Sravanthi
author_sort Hindustan Abdul Ahad
collection DOAJ
description The present work was to a comparative exploration of some physicochemical possessions viz., weight change, thickness, diameter, hardness, disintegration time, in-vitro drug discharge and analyse studies of various commercially available Pantoprazole sodium tablets (PST) of 40 mg. The hardness, loss on friability, dissolution test, disintegration test and uniformity of drug content were evaluated. All the brands meet the requirements as per the pharmacopoeial standards. The dissolution profile study revealed that PST-1 had faster while PST-2 has slower. The dissolution informations were kinetically treated.
format Article
id doaj-art-948b51b9ab664c9ab2481c649f10f2bf
institution Kabale University
issn 2307-4108
2307-4116
language English
publishDate 2020-12-01
publisher Elsevier
record_format Article
series Kuwait Journal of Science
spelling doaj-art-948b51b9ab664c9ab2481c649f10f2bf2025-08-20T03:26:43ZengElsevierKuwait Journal of Science2307-41082307-41162020-12-0148110.48129/kjs.v48i1.8598In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tabletsHindustan Abdul Ahad0Chinthaginjala Haranath1Rahul Raghav Dasari2Madana Gowthami3Naga Jyothi Varam4Pandyala Sravanthi5Dept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Ananthapuramu 515721, Andhra Pradesh, IndiaDept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Ananthapuramu 515721, Andhra Pradesh, IndiaDept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Ananthapuramu 515721, Andhra Pradesh, IndiaDept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Ananthapuramu 515721, Andhra Pradesh, IndiaDept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Ananthapuramu 515721, Andhra Pradesh, IndiaDept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Ananthapuramu 515721, Andhra Pradesh, India The present work was to a comparative exploration of some physicochemical possessions viz., weight change, thickness, diameter, hardness, disintegration time, in-vitro drug discharge and analyse studies of various commercially available Pantoprazole sodium tablets (PST) of 40 mg. The hardness, loss on friability, dissolution test, disintegration test and uniformity of drug content were evaluated. All the brands meet the requirements as per the pharmacopoeial standards. The dissolution profile study revealed that PST-1 had faster while PST-2 has slower. The dissolution informations were kinetically treated. https://journalskuwait.org/kjs/index.php/KJS/article/view/8598Pantoprazolebrandevolutionkinetics.
spellingShingle Hindustan Abdul Ahad
Chinthaginjala Haranath
Rahul Raghav Dasari
Madana Gowthami
Naga Jyothi Varam
Pandyala Sravanthi
In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets
Kuwait Journal of Science
Pantoprazole
brand
evolution
kinetics.
title In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets
title_full In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets
title_fullStr In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets
title_full_unstemmed In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets
title_short In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets
title_sort in vitro proportional investigation of different pantoprazole sodium brands of gastro resistant tablets
topic Pantoprazole
brand
evolution
kinetics.
url https://journalskuwait.org/kjs/index.php/KJS/article/view/8598
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AT rahulraghavdasari invitroproportionalinvestigationofdifferentpantoprazolesodiumbrandsofgastroresistanttablets
AT madanagowthami invitroproportionalinvestigationofdifferentpantoprazolesodiumbrandsofgastroresistanttablets
AT nagajyothivaram invitroproportionalinvestigationofdifferentpantoprazolesodiumbrandsofgastroresistanttablets
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