Current status of cytokine-induced killer cells and combination regimens in breast cancer
Breast cancer remains a significant health challenge worldwide, with substantial efforts aimed at understanding its pathogenesis, biological characteristics, and clinical triggers. Recently, immunotherapy such as the cytokine-induced killer cells combined with other drug therapies has offered new ho...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1476644/full |
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| _version_ | 1832087150155268096 |
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| author | Yuancong Jiang Jie Qiu Nanwei Ye Yingchun Xu |
| author_facet | Yuancong Jiang Jie Qiu Nanwei Ye Yingchun Xu |
| author_sort | Yuancong Jiang |
| collection | DOAJ |
| description | Breast cancer remains a significant health challenge worldwide, with substantial efforts aimed at understanding its pathogenesis, biological characteristics, and clinical triggers. Recently, immunotherapy such as the cytokine-induced killer cells combined with other drug therapies has offered new hope for patients with advanced breast cancer. However, the specific pathogenesis of combination regimens involving cytokine-induced killer cells remains elusive. Besides, the combination of immunotherapy with cytokine-induced killer cells might represent a novel breakthrough. This review outlines the current status of cytokine-induced killer cell therapies and their combination strategies, especially the combination of chemotherapy with molecularly targeted treatments, for the management of breast cancer. |
| format | Article |
| id | doaj-art-9484cff8c03c4f2195b667deaab13a24 |
| institution | Kabale University |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-9484cff8c03c4f2195b667deaab13a242025-02-06T07:09:41ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-02-011610.3389/fimmu.2025.14766441476644Current status of cytokine-induced killer cells and combination regimens in breast cancerYuancong Jiang0Jie Qiu1Nanwei Ye2Yingchun Xu3Department of Breast and Thyroid Surgery, Shaoxing People’s Hospital, Shaoxing, ChinaDepartment of Breast and Thyroid Surgery, Shaoxing People’s Hospital, Shaoxing, ChinaDepartment of Medical Research Center, Shaoxing People’s Hospital, Shaoxing, ChinaDepartment of Breast and Thyroid Surgery, Shaoxing People’s Hospital, Shaoxing, ChinaBreast cancer remains a significant health challenge worldwide, with substantial efforts aimed at understanding its pathogenesis, biological characteristics, and clinical triggers. Recently, immunotherapy such as the cytokine-induced killer cells combined with other drug therapies has offered new hope for patients with advanced breast cancer. However, the specific pathogenesis of combination regimens involving cytokine-induced killer cells remains elusive. Besides, the combination of immunotherapy with cytokine-induced killer cells might represent a novel breakthrough. This review outlines the current status of cytokine-induced killer cell therapies and their combination strategies, especially the combination of chemotherapy with molecularly targeted treatments, for the management of breast cancer.https://www.frontiersin.org/articles/10.3389/fimmu.2025.1476644/fullbreast cancercytokine-induced killer cellscombination therapiesimmunotherapymolecular targeted therapy |
| spellingShingle | Yuancong Jiang Jie Qiu Nanwei Ye Yingchun Xu Current status of cytokine-induced killer cells and combination regimens in breast cancer Frontiers in Immunology breast cancer cytokine-induced killer cells combination therapies immunotherapy molecular targeted therapy |
| title | Current status of cytokine-induced killer cells and combination regimens in breast cancer |
| title_full | Current status of cytokine-induced killer cells and combination regimens in breast cancer |
| title_fullStr | Current status of cytokine-induced killer cells and combination regimens in breast cancer |
| title_full_unstemmed | Current status of cytokine-induced killer cells and combination regimens in breast cancer |
| title_short | Current status of cytokine-induced killer cells and combination regimens in breast cancer |
| title_sort | current status of cytokine induced killer cells and combination regimens in breast cancer |
| topic | breast cancer cytokine-induced killer cells combination therapies immunotherapy molecular targeted therapy |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1476644/full |
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