Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran
HIV coinfected with other parasitic diseases may cause a serious problem for the patients. A few case reports describing echinococcosis with human immunodeficiency virus (HIV) infection have been reported in the world; however, it has not been reported in Iran, so far. Here, the first case of liver...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Canadian Journal of Gastroenterology and Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2021/8844104 |
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| author | Yosef Sharifi Seyed Mahmoud Sadjjadi Hamed Nikoupour Dailami Seyed Hamed Jafari Mohammad Hossein Anbardar Mohammad Bagher Khosravi |
| author_facet | Yosef Sharifi Seyed Mahmoud Sadjjadi Hamed Nikoupour Dailami Seyed Hamed Jafari Mohammad Hossein Anbardar Mohammad Bagher Khosravi |
| author_sort | Yosef Sharifi |
| collection | DOAJ |
| description | HIV coinfected with other parasitic diseases may cause a serious problem for the patients. A few case reports describing echinococcosis with human immunodeficiency virus (HIV) infection have been reported in the world; however, it has not been reported in Iran, so far. Here, the first case of liver hydatid cyst coinfected with HIV in Iran is reported. The patient is a 46-year-old female HIV-positive based on the laboratory report. Her clinical symptoms included abdominal pain, abdominal enlargement, and anorexia. Ultrasound showed three large hepatic hydatid cysts with hundreds of daughter cysts. Ultrasonography of the cyst revealed it as a CE2 stage according to the WHO classification. The patient went under complete anesthesia followed by complete cyst removal by surgery. Observation of the hydatid cyst fluid using eosin 0.1% revealed more than 70% viable protoscoleces. Histopathology examination, polymerase chain reaction (PCR), and viable protoscoleces confirmed the diagnosis of echinococcosis. The IgG ELISA test with native AgB for E. granulosus infection was also positive. mtDNA amplification using PCR and sequencing showed the cyst as E. granulosus sensu stricto genotype. Our observations show that huge, large, and high-pressure cysts with hundreds of daughter cysts are difficult to be completely removed, and drug treatment has not been able to reduce their size. Therefore, in HIV coinfection with hydatid cyst, surgery is preferable to other treatments. |
| format | Article |
| id | doaj-art-946423a7cc4d4fddb2994b4a3055a347 |
| institution | Kabale University |
| issn | 2291-2789 2291-2797 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology and Hepatology |
| spelling | doaj-art-946423a7cc4d4fddb2994b4a3055a3472025-02-03T05:51:11ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972021-01-01202110.1155/2021/88441048844104Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, IranYosef Sharifi0Seyed Mahmoud Sadjjadi1Hamed Nikoupour Dailami2Seyed Hamed Jafari3Mohammad Hossein Anbardar4Mohammad Bagher Khosravi5Department of Parasitology and Mycology, School of Medicine Shiraz University of Medical Sciences, Shiraz, IranDepartment of Parasitology and Mycology, School of Medicine Shiraz University of Medical Sciences, Shiraz, IranDepartment of Transplantation, Shiraz University of Medical Sciences, Shiraz, IranMedical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Pathology, Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Anesthesia, Shiraz Anesthesia and Critical Care Research Center, Shiraz, IranHIV coinfected with other parasitic diseases may cause a serious problem for the patients. A few case reports describing echinococcosis with human immunodeficiency virus (HIV) infection have been reported in the world; however, it has not been reported in Iran, so far. Here, the first case of liver hydatid cyst coinfected with HIV in Iran is reported. The patient is a 46-year-old female HIV-positive based on the laboratory report. Her clinical symptoms included abdominal pain, abdominal enlargement, and anorexia. Ultrasound showed three large hepatic hydatid cysts with hundreds of daughter cysts. Ultrasonography of the cyst revealed it as a CE2 stage according to the WHO classification. The patient went under complete anesthesia followed by complete cyst removal by surgery. Observation of the hydatid cyst fluid using eosin 0.1% revealed more than 70% viable protoscoleces. Histopathology examination, polymerase chain reaction (PCR), and viable protoscoleces confirmed the diagnosis of echinococcosis. The IgG ELISA test with native AgB for E. granulosus infection was also positive. mtDNA amplification using PCR and sequencing showed the cyst as E. granulosus sensu stricto genotype. Our observations show that huge, large, and high-pressure cysts with hundreds of daughter cysts are difficult to be completely removed, and drug treatment has not been able to reduce their size. Therefore, in HIV coinfection with hydatid cyst, surgery is preferable to other treatments.http://dx.doi.org/10.1155/2021/8844104 |
| spellingShingle | Yosef Sharifi Seyed Mahmoud Sadjjadi Hamed Nikoupour Dailami Seyed Hamed Jafari Mohammad Hossein Anbardar Mohammad Bagher Khosravi Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran Canadian Journal of Gastroenterology and Hepatology |
| title | Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran |
| title_full | Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran |
| title_fullStr | Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran |
| title_full_unstemmed | Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran |
| title_short | Cystic Echinococcosis/Hydatid Cyst Coinfection with HIV: A Report from Shiraz, Iran |
| title_sort | cystic echinococcosis hydatid cyst coinfection with hiv a report from shiraz iran |
| url | http://dx.doi.org/10.1155/2021/8844104 |
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