Evaluation of tumor-infiltrating lymphocytes and molecular alterations in advanced colorectal carcinoma: a retrospective study in Southern Brazil

Abstract Background Colorectal carcinoma (CRC) is a leading cause of cancer-related deaths globally, ranking second in mortality rates. Cancer progression is influenced not only by genetic mutations in tumour cells but also by the surrounding tumour microenvironment, which can promote tumour growth...

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Main Authors: Gabriela Remonatto, Emily Ferreira Salles Pilar, Fernanda De-Paris, Pedro Guilherme Schaefer, Lúcia Maria Kliemann
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Surgical and Experimental Pathology
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Online Access:https://doi.org/10.1186/s42047-024-00174-0
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