An Intact Dopamine Sensitivity in the Brain: A Necessity to Recover Hyperprolactinemia and Galactorrhea in a Female Hemodialysis Patient?
A female hemodialysis patient with galactorrhea due to hyperprolactinemia was treated with different dialysis modalities to assess the effect on prolactin levels. A single session of both high-flux hemodialysis and hemodiafiltration resulted in decreased prolactin levels (16,6% and 77,2%, resp.). Ho...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2017/3729629 |
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| author | Eva Philipse Ester Philipse Theodorus Twickler Amaryllis Van Craenenbroeck Marie Madeleine Couttenye Luc Van Gaal |
| author_facet | Eva Philipse Ester Philipse Theodorus Twickler Amaryllis Van Craenenbroeck Marie Madeleine Couttenye Luc Van Gaal |
| author_sort | Eva Philipse |
| collection | DOAJ |
| description | A female hemodialysis patient with galactorrhea due to hyperprolactinemia was treated with different dialysis modalities to assess the effect on prolactin levels. A single session of both high-flux hemodialysis and hemodiafiltration resulted in decreased prolactin levels (16,6% and 77,2%, resp.). However, baseline prolactin levels measured immediately before the next dialysis session did not change markedly. After cabergoline treatment was started, prolactin levels normalized and galactorrhea disappeared. Thus, dopaminergic inhibition of prolactin secretion might be reduced in patients with end-stage renal disease. This dopaminergic resistance could be an important mechanism of hyperprolactinemia in hemodialysis patients and its subsequent treatment strategies. |
| format | Article |
| id | doaj-art-944c3ffabb504ba1a2b71b33bc693f07 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-944c3ffabb504ba1a2b71b33bc693f072025-02-03T01:26:02ZengWileyCase Reports in Nephrology2090-66412090-665X2017-01-01201710.1155/2017/37296293729629An Intact Dopamine Sensitivity in the Brain: A Necessity to Recover Hyperprolactinemia and Galactorrhea in a Female Hemodialysis Patient?Eva Philipse0Ester Philipse1Theodorus Twickler2Amaryllis Van Craenenbroeck3Marie Madeleine Couttenye4Luc Van Gaal5Department of Endocrinology, University Hospital of Antwerp, Edegem, BelgiumDepartment of Nephrology, University Hospital of Antwerp, Edegem, BelgiumDepartment of Endocrinology, University Hospital of Antwerp, Edegem, BelgiumDepartment of Nephrology, University Hospital of Antwerp, Edegem, BelgiumDepartment of Nephrology, University Hospital of Antwerp, Edegem, BelgiumDepartment of Endocrinology, University Hospital of Antwerp, Edegem, BelgiumA female hemodialysis patient with galactorrhea due to hyperprolactinemia was treated with different dialysis modalities to assess the effect on prolactin levels. A single session of both high-flux hemodialysis and hemodiafiltration resulted in decreased prolactin levels (16,6% and 77,2%, resp.). However, baseline prolactin levels measured immediately before the next dialysis session did not change markedly. After cabergoline treatment was started, prolactin levels normalized and galactorrhea disappeared. Thus, dopaminergic inhibition of prolactin secretion might be reduced in patients with end-stage renal disease. This dopaminergic resistance could be an important mechanism of hyperprolactinemia in hemodialysis patients and its subsequent treatment strategies.http://dx.doi.org/10.1155/2017/3729629 |
| spellingShingle | Eva Philipse Ester Philipse Theodorus Twickler Amaryllis Van Craenenbroeck Marie Madeleine Couttenye Luc Van Gaal An Intact Dopamine Sensitivity in the Brain: A Necessity to Recover Hyperprolactinemia and Galactorrhea in a Female Hemodialysis Patient? Case Reports in Nephrology |
| title | An Intact Dopamine Sensitivity in the Brain: A Necessity to Recover Hyperprolactinemia and Galactorrhea in a Female Hemodialysis Patient? |
| title_full | An Intact Dopamine Sensitivity in the Brain: A Necessity to Recover Hyperprolactinemia and Galactorrhea in a Female Hemodialysis Patient? |
| title_fullStr | An Intact Dopamine Sensitivity in the Brain: A Necessity to Recover Hyperprolactinemia and Galactorrhea in a Female Hemodialysis Patient? |
| title_full_unstemmed | An Intact Dopamine Sensitivity in the Brain: A Necessity to Recover Hyperprolactinemia and Galactorrhea in a Female Hemodialysis Patient? |
| title_short | An Intact Dopamine Sensitivity in the Brain: A Necessity to Recover Hyperprolactinemia and Galactorrhea in a Female Hemodialysis Patient? |
| title_sort | intact dopamine sensitivity in the brain a necessity to recover hyperprolactinemia and galactorrhea in a female hemodialysis patient |
| url | http://dx.doi.org/10.1155/2017/3729629 |
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