Carbidopa/levodopa dose elevation and safety concerns in Parkinson's patients: a cross-sectional and cohort design
Objective Sinemet, a combination drug containing carbidopa and levodopa is considered the gold standard therapy for the treatment of Parkinson's disease (PD). When approved by the Food and Drug Administration (FDA) in 1988, a maximum daily dosage limit of 800 mg (eight tablets) of the 25/100 ca...
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Main Authors: | Michael S Okun, Peter Schmidt, David W Brodell, Nicole T Stanford, Charles E Jacobson |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2012-12-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/2/6/e001971.full |
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