Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease
Objective. This study aimed to evaluate the CT features of incidentally detected DTD in the patients who underwent thyroidectomy and to assess the diagnostic accuracy of CT diagnosis. Methods. We enrolled 209 consecutive patients who received preoperative neck CT and subsequent thyroid surgery. Neck...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/921934 |
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| author | Myung Ho Rho Dong Wook Kim |
| author_facet | Myung Ho Rho Dong Wook Kim |
| author_sort | Myung Ho Rho |
| collection | DOAJ |
| description | Objective. This study aimed to evaluate the CT features of incidentally detected DTD in the patients who underwent thyroidectomy and to assess the diagnostic accuracy of CT diagnosis. Methods. We enrolled 209 consecutive patients who received preoperative neck CT and subsequent thyroid surgery. Neck CT in each case was retrospectively investigated by a single radiologist. We evaluated the diagnostic accuracy of individual CT features and the cut-off CT criteria for detecting DTD by comparing the CT features with histopathological results. Results. Histopathological examination of the 209 cases revealed normal thyroid (n=157), Hashimoto thyroiditis (n=17), non-Hashimoto lymphocytic thyroiditis (n=34), and diffuse hyperplasia (n=1). The CT features suggestive of DTD included low attenuation, inhomogeneous attenuation, increased glandular size, lobulated margin, and inhomogeneous enhancement. ROC curve analysis revealed that CT diagnosis of DTD based on the CT classification of “3 or more” abnormal CT features was superior. When the “3 or more” CT classification was selected, the sensitivity, specificity, positive and negative predictive values, and accuracy of CT diagnosis for DTD were 55.8%, 95.5%, 80.6%, 86.7%, and 85.6%, respectively. Conclusion. Neck CT may be helpful for the detection of incidental DTD. |
| format | Article |
| id | doaj-art-943432f4935f4fc7977911a15e49cd8d |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-943432f4935f4fc7977911a15e49cd8d2025-02-03T01:06:56ZengWileyInternational Journal of Endocrinology1687-83371687-83452014-01-01201410.1155/2014/921934921934Computed Tomography Features of Incidentally Detected Diffuse Thyroid DiseaseMyung Ho Rho0Dong Wook Kim1Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 110-746, Republic of KoreaDepartment of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan 614-734, Republic of KoreaObjective. This study aimed to evaluate the CT features of incidentally detected DTD in the patients who underwent thyroidectomy and to assess the diagnostic accuracy of CT diagnosis. Methods. We enrolled 209 consecutive patients who received preoperative neck CT and subsequent thyroid surgery. Neck CT in each case was retrospectively investigated by a single radiologist. We evaluated the diagnostic accuracy of individual CT features and the cut-off CT criteria for detecting DTD by comparing the CT features with histopathological results. Results. Histopathological examination of the 209 cases revealed normal thyroid (n=157), Hashimoto thyroiditis (n=17), non-Hashimoto lymphocytic thyroiditis (n=34), and diffuse hyperplasia (n=1). The CT features suggestive of DTD included low attenuation, inhomogeneous attenuation, increased glandular size, lobulated margin, and inhomogeneous enhancement. ROC curve analysis revealed that CT diagnosis of DTD based on the CT classification of “3 or more” abnormal CT features was superior. When the “3 or more” CT classification was selected, the sensitivity, specificity, positive and negative predictive values, and accuracy of CT diagnosis for DTD were 55.8%, 95.5%, 80.6%, 86.7%, and 85.6%, respectively. Conclusion. Neck CT may be helpful for the detection of incidental DTD.http://dx.doi.org/10.1155/2014/921934 |
| spellingShingle | Myung Ho Rho Dong Wook Kim Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease International Journal of Endocrinology |
| title | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
| title_full | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
| title_fullStr | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
| title_full_unstemmed | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
| title_short | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
| title_sort | computed tomography features of incidentally detected diffuse thyroid disease |
| url | http://dx.doi.org/10.1155/2014/921934 |
| work_keys_str_mv | AT myunghorho computedtomographyfeaturesofincidentallydetecteddiffusethyroiddisease AT dongwookkim computedtomographyfeaturesofincidentallydetecteddiffusethyroiddisease |