Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control Study
It has been hypothesized that chronic renal failure (CRF) predisposes patients to infection with intestinal protozoa. We tested this hypothesis with a matched case-control study to determine the prevalence of these protozoa and their diarrhea associated symptoms among 50 patients with CRF (cases) fr...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/563478 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832545521774886912 |
|---|---|
| author | Yousry A. Hawash Laila Sh. Dorgham El-Amir M. Amir Osama F. Sharaf |
| author_facet | Yousry A. Hawash Laila Sh. Dorgham El-Amir M. Amir Osama F. Sharaf |
| author_sort | Yousry A. Hawash |
| collection | DOAJ |
| description | It has been hypothesized that chronic renal failure (CRF) predisposes patients to infection with intestinal protozoa. We tested this hypothesis with a matched case-control study to determine the prevalence of these protozoa and their diarrhea associated symptoms among 50 patients with CRF (cases) from Taif, western Saudi Arabia. Fifty diarrheal patients without CRF were recruited in the study as controls. Participants were interviewed by a structured questionnaire and stool samples were collected. Samples were thoroughly examined with microscopy and three coproantigens detection kits. Enteric protozoa were detected in 21 cases and 14 controls. Blastocystis spp. were the most predominant parasite (16% in cases versus 8% in controls), followed by Giardia duodenalis (10% in cases versus 12% in controls) and Cryptosporidium spp. (10% in cases versus 6% in controls). Cyclospora cayetanensis was identified in two cases, while Entamoeba histolytica was described in one case and one control. Intestinal parasitism was positively associated with the male gender, urban residence, and travel history. Clinical symptoms of nausea/vomiting and abdominal pain were significantly varied between the parasitized cases and controls (P value ≤ 0.05). Given the results, we recommend screening all diarrheal feces for intestinal protozoa in the study’s population, particularly those with CRF. |
| format | Article |
| id | doaj-art-93e6ee51aefb47808cc78866ccfb2a4c |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-93e6ee51aefb47808cc78866ccfb2a4c2025-02-03T07:25:33ZengWileyJournal of Tropical Medicine1687-96861687-96942015-01-01201510.1155/2015/563478563478Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control StudyYousry A. Hawash0Laila Sh. Dorgham1El-Amir M. Amir2Osama F. Sharaf3Department of Medical Laboratory Science, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi ArabiaDepartment of Community Medicine, National Liver Institute, Menoufia University, Shebin El-Koom, Menoufia 23513, EgyptDepartment of Medical Parasitology, National Liver Institute, Menoufia University, Shebin El-Koom, Menoufia 23513, EgyptDepartment of Medical Parasitology, National Liver Institute, Menoufia University, Shebin El-Koom, Menoufia 23513, EgyptIt has been hypothesized that chronic renal failure (CRF) predisposes patients to infection with intestinal protozoa. We tested this hypothesis with a matched case-control study to determine the prevalence of these protozoa and their diarrhea associated symptoms among 50 patients with CRF (cases) from Taif, western Saudi Arabia. Fifty diarrheal patients without CRF were recruited in the study as controls. Participants were interviewed by a structured questionnaire and stool samples were collected. Samples were thoroughly examined with microscopy and three coproantigens detection kits. Enteric protozoa were detected in 21 cases and 14 controls. Blastocystis spp. were the most predominant parasite (16% in cases versus 8% in controls), followed by Giardia duodenalis (10% in cases versus 12% in controls) and Cryptosporidium spp. (10% in cases versus 6% in controls). Cyclospora cayetanensis was identified in two cases, while Entamoeba histolytica was described in one case and one control. Intestinal parasitism was positively associated with the male gender, urban residence, and travel history. Clinical symptoms of nausea/vomiting and abdominal pain were significantly varied between the parasitized cases and controls (P value ≤ 0.05). Given the results, we recommend screening all diarrheal feces for intestinal protozoa in the study’s population, particularly those with CRF.http://dx.doi.org/10.1155/2015/563478 |
| spellingShingle | Yousry A. Hawash Laila Sh. Dorgham El-Amir M. Amir Osama F. Sharaf Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control Study Journal of Tropical Medicine |
| title | Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control Study |
| title_full | Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control Study |
| title_fullStr | Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control Study |
| title_full_unstemmed | Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control Study |
| title_short | Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control Study |
| title_sort | prevalence of intestinal protozoa among saudi patients with chronic renal failure a case control study |
| url | http://dx.doi.org/10.1155/2015/563478 |
| work_keys_str_mv | AT yousryahawash prevalenceofintestinalprotozoaamongsaudipatientswithchronicrenalfailureacasecontrolstudy AT lailashdorgham prevalenceofintestinalprotozoaamongsaudipatientswithchronicrenalfailureacasecontrolstudy AT elamirmamir prevalenceofintestinalprotozoaamongsaudipatientswithchronicrenalfailureacasecontrolstudy AT osamafsharaf prevalenceofintestinalprotozoaamongsaudipatientswithchronicrenalfailureacasecontrolstudy |