X-inactive-specific transcript: a long noncoding RNA with a complex role in sex differences in human disease
Abstract In humans, the X and Y chromosomes determine the biological sex, XX specifying for females and XY for males. The long noncoding RNA X-inactive specific transcript (lncRNA XIST) plays a crucial role in the process of X chromosome inactivation (XCI) in cells of the female, a process that ensu...
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| Main Authors: | Dan N. Predescu, Babak Mokhlesi, Sanda A. Predescu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
|
| Series: | Biology of Sex Differences |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13293-024-00681-5 |
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