X-inactive-specific transcript: a long noncoding RNA with a complex role in sex differences in human disease

Abstract In humans, the X and Y chromosomes determine the biological sex, XX specifying for females and XY for males. The long noncoding RNA X-inactive specific transcript (lncRNA XIST) plays a crucial role in the process of X chromosome inactivation (XCI) in cells of the female, a process that ensu...

Full description

Saved in:
Bibliographic Details
Main Authors: Dan N. Predescu, Babak Mokhlesi, Sanda A. Predescu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Biology of Sex Differences
Subjects:
Online Access:https://doi.org/10.1186/s13293-024-00681-5
Tags: Add Tag
No Tags, Be the first to tag this record!